Portfolio concentration
As of March 31, 2026 · N-PORT
Holdings
257
Top-10 weight
49.88%
Effective holdings
?
The number of equal-weight positions that would produce this portfolio's concentration (1 ÷ Herfindahl index). A 500-stock fund dominated by a few mega-caps might have only ~100 effective holdings.
29
Crowding
?
The value-weighted average number of funds that also own this fund's positions. High = consensus/crowded picks; low = holdings few other funds own.
736.4
Holdings
As of March 31, 2026 · N-PORT| # | Security | Ticker | Shares | Value | % of fund |
|---|---|---|---|---|---|
| 1 | BlackRock Cash Funds: Institutional, SL Agency Shares | BISXX | 784,655,767 | $784.81M | 9.66% |
| 2 | GILEAD SCIENCES INC | — | 4,515,707 | $629.35M | 7.75% |
| 3 | AMGEN INC | — | 1,733,148 | $609.81M | 7.51% |
| 4 | VERTEX PHARMACEUTICALS INC | — | 1,354,033 | $604.63M | 7.44% |
| 5 | REGENERON PHARMACEUTICALS INC | — | 758,232 | $585.84M | 7.21% |
| 6 | ALNYLAM PHARMACEUTICALS INC | — | 979,642 | $324.13M | 3.99% |
| 7 | INSMED INC | — | 1,587,887 | $259.65M | 3.20% |
| 8 | ARGENX SE SPONSORED ADR | — | 341,883 | $249.66M | 3.07% |
| 9 | BIOGEN INC | — | 1,091,046 | $200.02M | 2.46% |
| 10 | NATERA INC | — | 980,622 | $196.11M | 2.41% |
| 11 | UNITED THERAPEUTICS CORP DEL | — | 315,509 | $187.09M | 2.30% |
| 12 | BEONE MEDICINES LTD ADR | — | 529,143 | $157.14M | 1.93% |
| 13 | INCYTE CORP | — | 1,467,923 | $138.16M | 1.70% |
| 14 | MODERNA INC | — | 2,692,459 | $136.78M | 1.68% |
| 15 | ILLUMINA INC | — | 1,107,291 | $136.48M | 1.68% |
| 16 | REVOLUTION MEDICINES INC | — | 1,283,912 | $124.86M | 1.54% |
| 17 | ROIVANT SCIENCES LTD | — | 3,642,557 | $100.90M | 1.24% |
| 18 | NEUROCRINE BIOSCIENCES INC | — | 727,502 | $95.84M | 1.18% |
| 19 | GENMAB A/S -SP ADR DEPOSITARY RECEIPT | GMAB | 3,555,098 | $95.38M | 1.17% |
| 20 | BRIDGEBIO PHARMA INC | — | 1,238,687 | $91.98M | 1.13% |
| 21 | IONIS PHARMACEUTICALS INC | — | 1,205,549 | $90.52M | 1.11% |
| 22 | MEDPACE HOLDINGS INC | — | 169,922 | $81.59M | 1.00% |
| 23 | MADRIGAL PHARMACEUTICALS INC | — | 155,341 | $81.32M | 1.00% |
| 24 | EXELIXIS INC | — | 1,871,326 | $80.26M | 0.99% |
| 25 | BIOMARIN PHARMACEUTICAL INC | — | 1,412,330 | $79.78M | 0.98% |
| 26 | Ascendis Pharma A/S | — | 339,948 | $77.76M | 0.96% |
| 27 | PRAXIS PRECISION MEDICINES INC | — | 195,097 | $62.86M | 0.77% |
| 28 | CHARLES RIVER LABS INTL INC | — | 362,165 | $62.47M | 0.77% |
| 29 | ARROWHEAD PHARMACEUTICALS INC | — | 975,175 | $61.14M | 0.75% |
| 30 | VAXCYTE INC | — | 1,045,695 | $60.77M | 0.75% |
| 31 | BIO-TECHNE CORP | — | 1,151,950 | $60.20M | 0.74% |
| 32 | CYTOKINETICS INC | — | 896,972 | $59.12M | 0.73% |
| 33 | HALOZYME THERAPEUTICS INC | — | 868,502 | $56.13M | 0.69% |
| 34 | AXSOME THERAPEUTICS INC | — | 319,088 | $53.93M | 0.66% |
| 35 | BIONTECH SE ADR | — | 599,506 | $53.28M | 0.66% |
| 36 | KRYSTAL BIOTECH INC | — | 188,966 | $48.81M | 0.60% |
| 37 | PROTAGONIST THERAPEUTICS INC | — | 447,047 | $47.12M | 0.58% |
| 38 | REPLIGEN CORP | — | 396,896 | $46.76M | 0.58% |
| 39 | KYMERA THERAPEUTICS INC | — | 521,385 | $43.43M | 0.53% |
| 40 | ALKERMES PLC | — | 1,216,662 | $43.02M | 0.53% |
| 41 | RHYTHM PHARMACEUTICALS INC | — | 474,539 | $41.27M | 0.51% |
| 42 | Abivax SA SPONSORED ADS | ABVX US | 367,461 | $40.92M | 0.50% |
| 43 | PTC THERAPEUTICS INC | — | 593,152 | $40.41M | 0.50% |
| 44 | COGENT BIOSCIENCES INC | — | 1,009,396 | $38.85M | 0.48% |
| 45 | ARCELLX INC | — | 335,814 | $38.56M | 0.47% |
| 46 | TERNS PHARMACEUTICALS INC | — | 713,848 | $37.63M | 0.46% |
| 47 | NUVALENT INC-A | — | 355,481 | $36.42M | 0.45% |
| 48 | MIRUM PHARMACEUTICALS INC | — | 392,677 | $36.28M | 0.45% |
| 49 | TEMPUS AI INC-A | — | 773,906 | $35.00M | 0.43% |
| 50 | XENON PHARMACEUTICALS INC | — | 598,390 | $34.80M | 0.43% |
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