FundWatcher
SBIO
ALPS Medical Breakthroughs ETF
ALPS ETF TRUST
ETFIndex fund

Portfolio moves

Net position changes between two of this fund's N-PORT snapshots. These are differences between point-in-time reports — not a trade log — and share counts can be affected by splits and other corporate actions.

Nov 30, 2025 → Feb 28, 2026

Expand a category to see the positions behind it, ranked by weight.

Security Shares Nov 2025 Shares Feb 2026 Δ shares End % Δ value
KYMERA THERAPEUTICS INC 0 70,365 70,365 4.66% $6.43M
SPYRE THERAPEUTICS INC 0 69,157 69,157 2.15% $2.97M
MINERALYS THERAPEUTICS INC 0 70,537 70,537 1.49% $2.06M
SAREPTA THERAPEUTICS INC 0 93,395 93,395 1.13% $1.57M
OCULIS HOLDING AG 0 50,955 50,955 1.09% $1.50M
AMYLYX PHARMACEUTICALS INC 0 97,879 97,879 1.08% $1.48M
ORUKA THERAPEUTICS INC 0 43,144 43,144 1.08% $1.48M
SIONNA THERAPEUTICS INC 0 39,776 39,776 1.05% $1.45M
CORVUS PHARMACEUTICALS INC 0 66,564 66,564 0.88% $1.22M
TAYSHA GENE THERAPIES INC 0 244,138 244,138 0.80% $1.11M
ARRIVENT BIOPHARMA INC 0 36,792 36,792 0.61% $845.11K
KALVISTA PHARMACEUTICALS INC 0 45,051 45,051 0.53% $733.43K
ALTO NEUROSCIENCE INC 0 27,688 27,688 0.39% $545.18K
DESIGN THERAPEUTICS INC 0 50,771 50,771 0.38% $530.05K
ALTIMMUNE INC 0 92,999 92,999 0.29% $400.83K
TECTONIC THERAPEUTIC INC 0 16,682 16,682 0.28% $391.19K
ZURA BIO LTD COMMON STOCK USD.0001 0 57,952 57,952 0.28% $383.64K
FORTE BIOSCIENCES INC 0 11,166 11,166 0.24% $337.44K
NEUROGENE INC 0 13,806 13,806 0.23% $324.30K
PROTARA THERAPEUTICS INC 0 46,015 46,015 0.21% $292.66K
ACLARIS THERAPEUTICS INC 0 96,567 96,567 0.20% $277.15K
AARDVARK THERAPEUTICS INC 0 19,407 19,407 0.18% $242.39K
NOVO NORDISK A/S-CVR 0 1,233 1,233 0.00% $0
Security Shares Nov 2025 Shares Feb 2026 Δ shares End % Δ value
AVIDITY BIOSCIENCES 65,216 0 -65,216 0.00% -$4.68M
CYTOKINETICS INC 52,327 0 -52,327 0.00% -$3.57M
AXSOME THERAPEUTICS INC 22,591 0 -22,591 0.00% -$3.42M
RHYTHM PHARMACEUTICALS INC 30,477 0 -30,477 0.00% -$3.32M
ARROWHEAD PHARMACEUTICALS INC 60,236 0 -60,236 0.00% -$3.17M
MERUS NV 0.00000000 32,617 0 -32,617 0.00% -$3.14M
NUVALENT INC-A 28,495 0 -28,495 0.00% -$3.12M
PTC THERAPEUTICS INC 34,114 0 -34,114 0.00% -$2.93M
VAXCYTE INC 56,275 0 -56,275 0.00% -$2.79M
KRYSTAL BIOTECH INC 12,366 0 -12,366 0.00% -$2.70M
PROTAGONIST THERAPEUTICS INC 27,004 0 -27,004 0.00% -$2.43M
PRAXIS PRECISION MEDICINES INC 9,656 0 -9,656 0.00% -$1.90M
AKERO THERAPEUTICS INC 34,543 0 -34,543 0.00% -$1.88M
ARCELLX INC 23,254 0 -23,254 0.00% -$1.69M
ARCUS BIOSCIENCES INC 48,578 0 -48,578 0.00% -$1.27M
VIRIDIAN THERAPEUTICS INC 36,840 0 -36,840 0.00% -$1.18M
TERNS PHARMACEUTICALS INC 39,417 0 -39,417 0.00% -$1.11M
AURINIA PHARMS. INC 56,371 0 -56,371 0.00% -$908.70K
TREVI THERAPEUTICS INC 53,817 0 -53,817 0.00% -$709.85K
BIOCRYST PHARMACEUTICALS INC 93,421 0 -93,421 0.00% -$670.76K
IMMUNOME INC 36,238 0 -36,238 0.00% -$667.50K
UROGEN PHARMA LTD COMMON STOCK USD.01 20,632 0 -20,632 0.00% -$594.41K
ANAPTYSBIO INC 12,334 0 -12,334 0.00% -$513.71K
VIR BIOTECHNOLOGY INC 61,052 0 -61,052 0.00% -$391.95K
ERASCA INC 121,752 0 -121,752 0.00% -$385.95K
REPLIMUNE GROUP INC 34,830 0 -34,830 0.00% -$348.30K
KEROS THERAPEUTICS 18,062 0 -18,062 0.00% -$315.72K
ASTRIA THERAPEUTICS INC 24,204 0 -24,204 0.00% -$306.18K
GOSSAMER BIO INC 90,858 0 -90,858 0.00% -$303.47K
PROTHENA CORP PLC COMMON STOCK USD.01 23,727 0 -23,727 0.00% -$255.07K
COMPASS Pathways PLC, ADR 41,447 0 -41,447 0.00% -$230.03K
ANNEXON INC 43,983 0 -43,983 0.00% -$197.92K
Autolus Therapeutics PLC, ADR 114,538 0 -114,538 0.00% -$161.50K
CAPRICOR THERAPEUTICS INC 19,645 0 -19,645 0.00% -$105.10K
TONIX PHARMACEUTICALS HOLDING CORP 3,253 0 -3,253 0.00% -$51.95K
Security Shares Nov 2025 Shares Feb 2026 Δ shares End % Δ value
CELCUITY INC 18,484 41,241 22,757 3.34% $2.74M
ALKERMES PLC 71,953 147,168 75,215 3.21% $2.30M
CG ONCOLOGY INC 34,678 71,897 37,219 3.06% $2.67M
MIRUM PHARMACEUTICALS INC 22,211 45,804 23,593 3.06% $2.60M
AMICUS THERAPEUTICS INC 136,740 274,988 138,248 2.86% $2.59M
ACADIA PHARMACEUTICALS INC 74,317 150,789 76,472 2.68% $1.84M
NEWAMSTERDAM PHARMA CO NV COMMON STOCK 51,036 101,063 50,027 2.60% $1.48M
CRINETICS PHARMACEUTICALS INC 43,770 84,576 40,806 2.52% $1.48M
APOGEE THERAPEUTICS INC 20,762 48,872 28,110 2.48% $1.93M
VIKING THERAPEUTICS INC 50,644 100,746 50,102 2.47% $1.55M
STRUCTURE THERAPEUTICS INC ADR 25,792 54,083 28,291 2.47% $2.48M
XENON PHARMACEUTICALS INC 34,396 68,873 34,477 2.16% $1.44M
EDGEWISE THERAPEUTICS INC 47,245 94,360 47,115 2.08% $1.64M
TARSUS PHARMACEUTICALS INC 19,829 37,835 18,006 2.07% $1.27M
DENALI THERAPEUTICS INC 64,726 131,033 66,307 2.01% $1.52M
IDEAYA BIOSCIENCES 38,786 78,135 39,349 1.82% $1.13M
TRAVERE THERAPEUTICS INC 43,606 79,744 36,138 1.72% $831.49K
APELLIS PHARMACEUTICALS INC 58,034 112,768 54,734 1.71% $1.13M
VERA THERAPEUTICS INC 28,383 56,977 28,594 1.68% $1.37M
DISC MEDICINE INC 15,503 33,646 18,143 1.62% $794.14K
DIANTHUS THERAPEUTICS INC 14,474 38,214 23,740 1.53% $1.47M
GALAPAGOS GENOMICS NV SPON AR 29,514 58,387 28,873 1.42% $1.04M
MAZE THERAPEUTICS INC 12,697 42,889 30,192 1.42% $1.48M
ZAI LAB LTD UNSPNRD ADR 48,584 99,972 51,388 1.39% $929.86K
STOKE THERAPEUTICS INC 23,269 50,908 27,639 1.34% $1.13M
NUVATION BIO INC 152,082 305,559 153,477 1.31% $584.64K
CELLDEX THERAPEUTICS INC 29,518 59,226 29,708 1.29% $984.53K
OLEMA PHARMACEUTICALS INC 30,038 70,109 40,071 1.23% $845.96K
PHARVARIS NV COMMON STOCK EUR.12 28,380 57,094 28,714 1.17% $815.47K
VERICEL CORP 21,069 45,076 24,007 1.16% $760.28K
RELAY THERAPEUTICS INC 75,919 154,480 78,561 1.15% $983.69K
TYRA BIOSCIENCES INC 22,820 47,570 24,750 1.15% $1.07M
AGIOS PHARMACEUTICALS INC 25,453 51,973 26,520 1.14% $827.92K
NOVAVAX INC 69,812 144,833 75,021 1.06% $976.43K
Immunocore Holdings plc ADS 22,504 45,035 22,531 1.05% $565.72K
PALVELLA THERAPEUTICS INC 5,064 10,552 5,488 1.03% $904.20K
MBX BIOSCIENCES INC 15,540 40,022 24,482 0.94% $766.74K
ZENAS BIOPHARMA INC 18,476 47,842 29,366 0.91% $543.21K
IMMATICS NV COMMON STOCK 53,445 119,488 66,043 0.89% $664.18K
RAPPORT THERAPEUTICS INC 15,769 42,477 26,708 0.89% $764.61K
MOONLAKE IMMUNOTHERAPEUTICS 28,389 63,143 34,754 0.80% $715.85K
DAY ONE BIOPHARMACEUTICALS INC 44,903 91,514 46,611 0.70% $543.92K
GERON CORP 279,271 568,951 289,680 0.69% $626.30K
MANNKIND CORP 141,314 273,687 132,373 0.65% $141.66K
COMPASS THERAPEUTICS INC 76,438 158,523 82,085 0.65% $452.31K
THERAVANCE B 22,478 45,164 22,686 0.60% $367.94K
BICARA THERAPEUTICS INC 24,399 48,826 24,427 0.59% $366.45K
ARS PHARMACEUTICALS INC 45,490 88,100 42,610 0.59% $383.59K
XENCOR INC 31,389 63,648 32,259 0.59% $269.13K
KURA ONCOLOGY INC 35,992 77,558 41,566 0.49% $240.14K
RIGEL PHARMACEUTICALS INC 7,738 16,180 8,442 0.41% $171.40K
VANDA PHARMACEUTICALS INC 24,780 52,672 27,892 0.34% $336.49K
FULGENT GENETICS INC 13,395 27,554 14,159 0.31% $26.18K
REGENXBIO INC 22,838 45,118 22,280 0.30% $102.07K
UPSTREAM BIO INC 24,027 48,162 24,135 0.27% -$317.29K
ANAVEX LIFE SCIENCES CORP 35,659 79,635 43,976 0.26% $216.21K
ATEA PHARMACEUTICALS INC 32,596 69,634 37,038 0.24% $224.84K
AKEBIA THERAPEUTICS INC 116,038 236,514 120,476 0.22% $126.49K
DELCATH SYSTEMS 15,563 31,472 15,909 0.20% $129.14K
REZOLUTE INC 39,450 82,647 43,197 0.19% -$118.16K
CANDEL THERAPEUTICS INC 24,110 48,929 24,819 0.19% $141.87K
Bicycle Therapeutics PLC SPONSORED ADS 22,302 44,503 22,201 0.18% $88.18K
ARCTURUS THERAPEUTICS HOLDINGS INC 11,814 25,324 13,510 0.15% $128.20K
Security Shares Nov 2025 Shares Feb 2026 Δ shares End % Δ value
State Street Institutional Treasury Plus Money Market Fund- Premier Class 54,205 50,717 -3,488 0.04% -$3.49K
US ULTRA BOND CBT Sep25 28,640 0 -28,640 0.00% -$0
Security Shares Nov 2025 Shares Feb 2026 Δ shares End % Δ value
ASTRAZENECA PLC CVR RT 36,586 36,586 0 0.00% $0
CHINOOK THERAPEUTICS INC CVR RT 20,700 20,700 0 0.00% $0
OMNIAB INC - 12.5 EARNOUT 3,653 3,653 0 0.00% $0
OMNIAB INC - 15.00 EARNOUT 3,653 3,653 0 0.00% $0

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