PBE
Invesco Biotechnology & Genome ETF
Invesco Exchange-Traded Fund Trust
ETFIndex fund
Expense ratio1
0.58%
Net assets2
$262.98M
Holdings2
33
Category
US Equity
2025 return3
24.72%

Investment objective & strategy

As of Aug. 27, 2025 · prospectus

Objective. The Invesco Biotechnology & Genome ETF (the Fund) seeks to track the investment results (before fees and expenses) of the Dynamic Biotech & Genome Intellidex Index (the Underlying Index).

Strategy. The Fund generally will invest at least 90% of its total assets in securities that comprise the Underlying Index. Strictly in accordance with its guidelines and mandated procedures, ICE Data Indices, LLC (ICE Data or the Index Provider) compiles and maintains the Underlying Index, which is composed of common stocks of 30 U.S. biotechnology and genome companies. These companies are engaged principally in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes, and are companies that benefit significantly from scientific and technological advances in biotechnology and genetic engineering and research. These companies may include biopharmaceutical companies that actively participate in the research and development, animal testing and partial human testing phases of drug development, … The Fund generally will invest at least 90% of its total assets in securities that comprise the Underlying Index. Strictly in accordance with its guidelines and mandated procedures, ICE Data Indices, LLC (ICE Data or the Index Provider) compiles and maintains the Underlying Index, which is composed of common stocks of 30 U.S. biotechnology and genome companies. These companies are engaged principally in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes, and are companies that benefit significantly from scientific and technological advances in biotechnology and genetic engineering and research. These companies may include biopharmaceutical companies that actively participate in the research and development, animal testing and partial human testing phases of drug development, typically using biotechnological techniques that require the use of living organisms, cells and/or components of cells; outsourced services companies that utilize drug delivery technologies in the development of therapeutics for the biopharmaceutical industry or provide biopharmaceutical companies with novel biological targets and drug leads, and scientific products such as bio-analytical instruments, reagents, and chemicals. As of June 30, 2025, the Underlying Index was comprised of 30 constituents with market capitalizations ranging from $787.1 million to $150.1 billion. The Fund employs a full replication methodology in seeking to track the Underlying Index, meaning that the Fund generally invests in all of the securities comprising the Underlying Index in proportion to their weightings in the Underlying Index. The Fund is non-diversified and therefore is not required to meet certain diversification requirements under the Investment Company Act of 1940, as amended (the 1940 Act). Concentration Policy. The Fund will concentrate its investments (i.e., invest 25% or more of the value of its total assets) in securities of issuers in any one industry or group of industries only to the extent that the Underlying Index reflects a concentration in that industry or group of industries. The Fund will not otherwise concentrate its investments in securities of issuers in any one industry or group of industries. As of April 30, 2025, the Fund had significant exposure to the biotechnology and genome industry. The Funds portfolio holdings, and the extent to which it concentrates its investments, are likely to change over time.

Top holdings

As of Jan. 31, 2026 · N-PORT
SecurityTickerValue% of fund
Invesco Private Prime Fund $26.78M 10.18%
ILLUMINA INC $14.94M 5.68%
GILEAD SCIENCES INC $14.73M 5.60%
AMGEN INC $13.29M 5.06%
BIOGEN INC $13.22M 5.03%
UNITED THERAPEUTICS CORP DEL $12.79M 4.86%
REGENERON PHARMACEUTICALS INC $12.66M 4.81%
INCYTE CORP $12.24M 4.66%
Invesco Private Government Fund $10.31M 3.92%
AMICUS THERAPEUTICS INC $10.25M 3.90%
View all holdings →

Allocation by sector

As of January 31, 2026 · N-PORT
View portfolio breakdown →

Portfolio moves

Oct 31, 2025 → Jan 31, 2026
Opened
6
Exited
6
Increased
17
Decreased
10
Unchanged
0

How many positions this fund opened, exited, grew, trimmed, or left unchanged between its two most recent N-PORT snapshots — net changes between point-in-time reports, not a trade log.

View portfolio moves →

Similar funds

Funds whose portfolios most overlap this one, by weight
FundOverlapNet exp.
First Trust NYSE Arca Biotechnology Index Fund · FBT 46% 0.54%
Invesco Nasdaq Biotechnology ETF · IBBQ 42% 0.19%
Biotechnology Fund · RYOIX, RYOAX, RYBOX, RYCFX 35% 1.40%
View all similar funds →

Advisers

As of April 30, 2025 · N-CEN
FirmRole
Invesco Capital Management LLC Adviser

Footnotes

  1. Expense ratio as of August 27, 2025, from the fund's prospectus.
  2. Net assets and holdings count as of January 31, 2026, from the fund's N-PORT filing.
  3. Total return for calendar year 2025, before tax and after fund expenses. Computed by compounding the twelve monthly total returns the fund reported in its SEC N-PORT filings for 2025 (the latest prospectus does not yet chart this year).

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