MSHMX
Permanence Portfolio
MORGAN STANLEY INSTITUTIONAL FUND INC
Expense ratio1
0.85%
Net assets2
$3.83M
Holdings2
79
Category
US Equity
2025 return3
18.20%

Investment objective & strategy

As of April 30, 2025 · prospectus

Objective. The Permanence Portfolio (the Fund) seeks long-term capital appreciation.

Strategy. Under normal market conditions, the Adviser seeks to achieve the Funds investment objective by investing primarily in equity securities of established companies located in the United States, with capitalizations within the range of companies included in the S&P 500 Index. ? The Adviser emphasizes a bottom-up stock selection process, seeking attractive investments on an individual company basis. In selecting securities for investment, the Adviser typically invests in companies it believes have strong name recognition and sustainable competitive advantages with above average business visibility, the ability to deploy capital at high rates of return, strong balance sheets and an attractive risk/reward. The Adviser typically focuses a significant portion of the Funds investments in a limited number of issuers, which may be … Under normal market conditions, the Adviser seeks to achieve the Funds investment objective by investing primarily in equity securities of established companies located in the United States, with capitalizations within the range of companies included in the S&P 500 Index. ? The Adviser emphasizes a bottom-up stock selection process, seeking attractive investments on an individual company basis. In selecting securities for investment, the Adviser typically invests in companies it believes have strong name recognition and sustainable competitive advantages with above average business visibility, the ability to deploy capital at high rates of return, strong balance sheets and an attractive risk/reward. The Adviser typically focuses a significant portion of the Funds investments in a limited number of issuers, which may be in the same industry, sector or geographic region. The Fund will make long-term investments in companies that the Adviser believes have the most durable long-term competitive advantages. ?The Fund may also invest in more moderate growth companies, companies with lower earnings volatility and/or companies with some cyclicality in their end markets. ? The Adviser actively integrates sustainability into the investment process by using environmental, social and governance (ESG) factors as a lens for additional fundamental research, which can contribute to investment decision-making. The Adviser seeks to understand how environmental and social initiatives within companies can create value by strengthening durable competitive advantages, creating growth opportunities, driving profitability and/or aligning with secular growth trends. The Adviser generally engages with company management teams to discuss their ESG practices, with the aim of identifying how sustainability themes present opportunities and risks that can be material to the value of the security over the long-term. Other aspects of the investment process include a proprietary, systematic evaluation of governance policies, specifically focusing on compensation alignment on long- term value creation. ?Although consideration of ESG factors is incorporated into the investment process, it is only one of many tools the Adviser utilizes to make investment decisions. The Fund may invest in foreign securities, which may include emerging market securities. ?

Top holdings

As of March 31, 2026 · N-PORT
SecurityTickerValue% of fund
CLOUDFLARE INC-A $526.37K 13.74%
ROYALTY PHARMA PLC $317.95K 8.30%
QXO INC $244.46K 6.38%
MSILF-TR SEC-INS MSUXX $202.10K 5.28%
MEDLINE INC-A $189.30K 4.94%
CORE & MAIN IN-A $168.50K 4.40%
SPOTIFY TECHNOLOGY SA $153.23K 4.00%
COPART INC $132.80K 3.47%
VERISK ANALYTICS INC $132.45K 3.46%
MSCI INC $129.90K 3.39%
View all holdings →

Allocation by sector

As of March 31, 2026 · N-PORT
View portfolio breakdown →

Portfolio moves

Dec 31, 2025 → Mar 31, 2026
Opened
18
Exited
8
Increased
7
Decreased
53
Unchanged
2

How many positions this fund opened, exited, grew, trimmed, or left unchanged between its two most recent N-PORT snapshots — net changes between point-in-time reports, not a trade log.

View portfolio moves →

Similar funds

Funds whose portfolios most overlap this one, by weight
FundOverlapNet exp.
Global Permanence Portfolio · MGKQX, MGKAX, MGKCX, MGKIX 66% 0.95%
Advantage Portfolio · MPAIX, MAPLX, MAPPX, MADSX, MSPRX 59% 0.81%
Growth Portfolio · MEGIX, MEGTX 51% 0.57%
View all similar funds →

Advisers

As of December 31, 2025 · N-CEN
FirmRole
Morgan Stanley Investment Management Inc. Adviser

Footnotes

  1. Expense ratio as of April 30, 2025, from the fund's prospectus.
  2. Net assets and holdings count as of March 31, 2026, from the fund's N-PORT filing.
  3. Total return for calendar year 2025, before tax and after fund expenses. Computed by compounding the twelve monthly total returns the fund reported in its SEC N-PORT filings for 2025 (the latest prospectus does not yet chart this year).

Machine-readable: JSON · Markdown. Programmatic access via the agent surface.