LYFCX
AlphaCentric Life Sciences and Healthcare Fund
MUTUAL FUND SERIES TRUST
Expense ratio1
2.46%
Net assets2
$39.32M
Holdings2
62
Category
US Equity
2025 return3
26.96%

Investment objective & strategy

As of July 28, 2025 · prospectus

Objective. The Fund?s investment objective is long-term capital appreciation.

Strategy. The Fund seeks to achieve its investment objective by investing in the life sciences and healthcare related companies that the Fund?s investment sub-advisor, Kennedy Capital Management LLC (the ?Sub-Advisor?), believes have the potential to appreciate in value. Under normal market conditions, the Fund invests at least 80% of its net assets plus borrowings for investment purposes in the securities of companies in the life sciences and healthcare sectors , which the Fund defines to be the category of companies related to producing or supplying facilities, supplies, technology, pharmaceuticals, equipment, devices or services for the preservation and care of a person?s or animal?s health . The Fund invests in equity securities, primarily common stock, of these companies and may also invest, … The Fund seeks to achieve its investment objective by investing in the life sciences and healthcare related companies that the Fund?s investment sub-advisor, Kennedy Capital Management LLC (the ?Sub-Advisor?), believes have the potential to appreciate in value. Under normal market conditions, the Fund invests at least 80% of its net assets plus borrowings for investment purposes in the securities of companies in the life sciences and healthcare sectors , which the Fund defines to be the category of companies related to producing or supplying facilities, supplies, technology, pharmaceuticals, equipment, devices or services for the preservation and care of a person?s or animal?s health . The Fund invests in equity securities, primarily common stock, of these companies and may also invest, from time to time, in exchange traded funds (?ETFs?) that primarily invest in these companies. The Fund defines life sciences and healthcare companies to include those companies that are expected to derive 50% or more of their revenue from life sciences and healthcare related products and services. These companies may include development stage companies, which are entities devoting substantially all of their efforts to establishing a business for which commercial operations have not commenced or no significant revenue is being generated. The Fund may invest up to 15% of the Fund?s net assets in private and other companies whose securities may have legal or contractual restrictions on resale or are otherwise illiquid such as initial public offerings (?IPOs?), mezzanine financing offerings and other structured transactions. The Fund may invest in securities of companies of any market capitalization and in foreign companies, either directly or through American Depositary Receipts (?ADRs?). The Fund concentrates its investments (i.e., invests more than 25% of its assets) in the biotech and pharmaceutical; health care facilities and services; and medical equipment and devices industries, collectively. Each of these industries are commonly categorized within the healthcare sector because they share similar distribution channels and regulatory constraints. For hedging purposes, or when the Sub-Advisor anticipates significant price changes due to company or market moving events, the Fund may also invest in inverse ETFs and purchase and sell call and put options on equity securities of life sciences and healthcare companies. The Sub-Advisor begins the investment selection process by systematically screening the universe of life sciences and healthcare companies using fundamental scientific and medical literature review, and input from leading scientific and medical experts, to identify highly innovative thematic areas of interest. Financial analysis, market projections and corporate diligence are then performed to select the Fund?s investments. The Fund actively trades its portfolio investments, which may lead to higher transaction costs that may affect the Fund?s performance.

Top holdings

As of March 31, 2026 · N-PORT
SecurityTickerValue% of fund
FIRST AM-TR OB-X TMPXX $3.04M 7.72%
GILEAD SCIENCES INC $2.82M 7.18%
AstraZeneca PLC ORD USD0.25 AZN LN $2.22M 5.63%
VERTEX PHARMACEUTICALS INC $2.20M 5.60%
IONIS PHARMACEUTICALS INC $1.47M 3.74%
INSMED INC $1.40M 3.57%
INCYTE CORP $1.34M 3.41%
ROIVANT SCIENCES $1.32M 3.36%
ARGENX SE SPONSORED ADR $1.31M 3.33%
NEUROCRINE BIOSCIENCES INC $1.27M 3.22%
View all holdings →

Allocation by sector

As of March 31, 2026 · N-PORT
View portfolio breakdown →

Portfolio moves

Dec 31, 2025 → Mar 31, 2026
Opened
11
Exited
10
Increased
48
Decreased
4
Unchanged
0

How many positions this fund opened, exited, grew, trimmed, or left unchanged between its two most recent N-PORT snapshots — net changes between point-in-time reports, not a trade log.

View portfolio moves →

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Funds whose portfolios most overlap this one, by weight
FundOverlapNet exp.
iShares Biotechnology ETF · IBB 36% 0.44%
Biotechnology Fund · RYOIX, RYOAX, RYBOX, RYCFX 36% 1.40%
Biotechnology Fund 36% 1.74%
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Advisers

As of March 31, 2025 · N-CEN
FirmRole
Kennedy Capital Management LLC Sub-adviser
AlphaCentric Advisors LLC Adviser

Footnotes

  1. Expense ratio as of July 28, 2025, from the fund's prospectus.
  2. Net assets and holdings count as of March 31, 2026, from the fund's N-PORT filing.
  3. Total return for calendar year 2025, before tax and after fund expenses. Computed by compounding the twelve monthly total returns the fund reported in its SEC N-PORT filings for 2025 (the latest prospectus does not yet chart this year).

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