Portfolio moves
Net position changes between two of this fund's N-PORT
snapshots. These are differences between point-in-time reports — not a
trade log — and share counts can be affected by splits and other corporate
actions.
Dec 31, 2025 → Mar 31, 2026
Expand a category to
see the positions behind it, ranked by weight.
▶
Opened
· 9 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
Roche Holding AG CHF0.001
0
290,904
290,904
2.21%
$114.90M
MERCK & CO
0
638,574
638,574
1.48%
$76.81M
Janus Henderson Cash Liquidity Fund LLC
0
20,152,770
20,152,770
0.39%
$20.15M
BIOHAVEN LTD
0
2,220,238
2,220,238
0.36%
$18.78M
HEARTFLOW INC
0
585,648
585,648
0.27%
$14.25M
Mirum Pharmaceuticals Inc
0
123,782
123,782
0.22%
$11.43M
CONTRA AVADEL PHARMACE
0
450,200
450,200
0.01%
$288.13K
Japan Yen Cash Balance
0
21,344
21,344
0.00%
$21.34K
Euro Member Countries Cash Balance
0
287
287
0.00%
$287
▶
Exited
· 13 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
ROCHE HLDG-GENUS
275,465
0
-275,465
0.00%
-$113.87M
AVIDITY BIOSCIENCES
733,241
0
-733,241
0.00%
-$52.89M
Janus Henderson Cash Liquidity Fund LLC
40,171,471
0
-40,171,471
0.00%
-$40.18M
HeartFlow Inc - Series F
662,334
0
-662,334
0.00%
-$19.31M
Janus Henderson Cash Collateral Fund
18,730,800
0
-18,730,800
0.00%
-$18.73M
INSMED INC
80,434
0
-80,434
0.00%
-$14.00M
INSPIRE MEDICAL SYSTEMS INC
144,942
0
-144,942
0.00%
-$13.37M
ARCELLX INC
204,283
0
-204,283
0.00%
-$13.32M
AVADEL PHARMACEU
476,744
0
-476,744
0.00%
-$10.27M
US ULTRA BOND CBT Sep25
4,682,700
0
-4,682,700
0.00%
-$4.68M
HeartFlow Inc
131,576
0
-131,576
0.00%
-$3.84M
ALIGN TECHNOLOGY INC
7,287
0
-7,287
0.00%
-$1.14M
HeartFlow Inc
13,699
0
-13,699
0.00%
-$399.33K
▶
Increased
· 43 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
LILLY ELI and CO
481,268
499,479
18,211
8.85%
-$57.80M
JOHNSON&JOHNSON
1,444,532
1,550,240
105,708
7.30%
$79.99M
ABBVIE INC
794,492
967,983
173,491
4.06%
$28.99M
UNITEDHEALTH GRP
557,669
601,241
43,572
3.14%
-$21.40M
THERMO FISHER SCIENTIFIC INC
212,153
265,275
53,122
2.51%
$7.46M
ARGENX SE SPONSORED ADR
167,389
170,830
3,441
2.40%
-$16.02M
ABBOTT LABS
1,130,599
1,212,497
81,898
2.40%
-$17.17M
BRIDGEBIO PHARMA INC
1,477,488
1,551,141
73,653
2.22%
$2.17M
INTUITIVE SURGICAL INC
217,842
227,319
9,477
2.02%
-$18.59M
BOSTON SCIENTIFIC CORP
1,318,073
1,520,117
202,044
1.84%
-$30.29M
STRYKER CORP
249,313
260,843
11,530
1.65%
-$1.92M
DANAHER CORP
415,394
448,567
33,173
1.64%
-$10.04M
MADRIGAL PHARMACEUTICALS INC
131,174
149,195
18,021
1.51%
$1.71M
CVS HEALTH CORP
1,021,515
1,071,894
50,379
1.48%
-$4.08M
PTC THERAPEUTICS INC
764,689
1,024,173
259,484
1.34%
$11.69M
UNITED THERAPEUTICS CORP DEL
106,924
116,721
9,797
1.33%
$17.11M
MIRUM PHARMACEUTICALS INC
682,692
685,482
2,790
1.22%
$9.40M
DYNE THERAPEUTICS INC
2,519,217
2,528,224
9,007
0.88%
-$3.44M
EDWARDS LIFESCIENCES CORP
462,871
465,579
2,708
0.72%
-$2.18M
DEXCOM INC
423,924
561,491
137,567
0.68%
$7.13M
APOGEE THERAPEUTICS INC
378,258
379,608
1,350
0.62%
$3.40M
BECTON DICKINSON and CO
166,928
181,577
14,649
0.55%
-$3.85M
GLAUKOS CORP
219,939
264,704
44,765
0.55%
$3.66M
TARSUS PHARMACEUTICALS INC
275,745
296,425
20,680
0.40%
-$1.78M
EDGEWISE THERAPEUTICS INC
617,627
659,507
41,880
0.40%
$5.45M
XENON PHARMACEUTICALS INC
312,636
348,546
35,910
0.39%
$6.26M
COGENT BIOSCIENCES INC
408,854
498,576
89,722
0.37%
$4.67M
REGENERON PHARMACEUTICALS INC
23,929
23,991
62
0.36%
$66.33K
STERIS PLC
81,625
81,916
291
0.35%
-$2.58M
PROTAGONIST THERAPEUTICS INC
159,730
160,299
569
0.33%
$2.94M
SCHOLAR ROCK HOLDING CORP
340,484
341,699
1,215
0.32%
$1.80M
ALNYLAM PHARMACEUTICALS INC
45,828
45,992
164
0.29%
-$3.01M
SOTERA HEALTH CO
1,054,251
1,058,022
3,771
0.29%
-$3.42M
CRINETICS PHARMACEUTICALS INC
299,801
394,286
94,485
0.28%
$364.73K
ILLUMINA INC
101,851
102,214
363
0.24%
-$759.88K
INSULET CORP
36,426
59,223
22,797
0.24%
$2.07M
CENTENE CORP
339,642
340,855
1,213
0.22%
-$2.82M
JANUX THERAPEUTICS INC
719,025
720,074
1,049
0.19%
$86.48K
OLEMA PHARMACEUTICALS INC
666,913
669,297
2,384
0.19%
-$6.69M
HUMANA INC
52,553
52,740
187
0.18%
-$4.32M
IMMUNOME INC
368,171
368,708
537
0.16%
$155.33K
4D MOLECULAR THERAPEUTICS INC
842,520
843,751
1,231
0.15%
$1.54M
LEXEO THERAPEUTICS INC
632,552
633,486
934
0.07%
-$2.65M
▶
Decreased
· 35 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
AstraZeneca PLC ORD USD0.25
1,240,485
1,221,946
-18,539
4.60%
$10.19M
Novartis AG
971,981
971,619
-362
2.86%
$14.41M
PRAXIS PRECISION MEDICINES INC
433,759
394,970
-38,789
2.45%
-$590.74K
SANOFI
1,261,100
1,116,972
-144,128
2.08%
-$14.61M
VERTEX PHARMACEUTICALS INC
240,492
239,922
-570
2.06%
-$1.89M
REVOLUTION MEDICINES INC
1,294,495
1,088,018
-206,477
2.04%
$2.70M
HCA HEALTHCARE INC
224,626
206,592
-18,034
1.88%
-$7.10M
AMGEN INC
351,048
270,089
-80,959
1.83%
-$19.87M
Ascendis Pharma A/S
375,734
375,183
-551
1.65%
$5.69M
MCKESSON CORP
83,343
79,818
-3,525
1.33%
$705.88K
GILEAD SCIENCES INC
478,997
471,681
-7,316
1.27%
$6.95M
GLOBUS MEDICAL INC
753,721
748,604
-5,117
1.24%
-$1.31M
TEVA PHARMACEUTICAL IND ADR
2,045,096
2,037,481
-7,615
1.18%
-$2.46M
VAXCYTE INC
973,715
971,737
-1,978
1.09%
$11.54M
MEDTRONIC PLC
644,860
583,432
-61,428
0.97%
-$11.39M
ELEVANCE HEALTH INC
168,990
165,285
-3,705
0.93%
-$10.85M
CENCORA INC
161,927
139,138
-22,789
0.84%
-$10.98M
TRAVERE THERAPEUTICS INC
1,437,191
1,432,164
-5,027
0.82%
-$12.37M
LANTHEUS HOLDING
525,258
518,786
-6,472
0.76%
$4.39M
MEDLINE INC-A
879,124
864,511
-14,613
0.74%
$1.55M
SOLENO THERAPEUTICS INC
1,001,983
987,780
-14,203
0.64%
-$13.32M
UCB SA
131,102
104,561
-26,541
0.61%
-$5.07M
STRUCTURE THERAPEUTICS INC ADR
574,288
569,589
-4,699
0.53%
-$12.49M
IDEAYA BIOSCIENCES
763,325
738,748
-24,577
0.47%
-$1.77M
PENUMBRA INC
100,121
73,736
-26,385
0.47%
-$6.92M
COOPER COS INC
321,068
281,740
-39,328
0.39%
-$6.17M
Daiichi Sankyo Company Ltd.
1,647,700
1,047,000
-600,700
0.36%
-$16.64M
NEUROCRINE BIOSCIENCES INC
138,796
136,901
-1,895
0.35%
-$1.65M
ZOETIS INC CL A
134,911
131,945
-2,966
0.30%
-$1.38M
ARDELYX INC
3,109,866
2,595,821
-514,045
0.30%
-$2.58M
RHYTHM PHARMACEUTICALS INC
191,235
160,804
-30,431
0.27%
-$6.48M
NUVALENT INC-A
186,488
128,313
-58,175
0.25%
-$5.61M
TELEFLEX INC
101,052
97,944
-3,108
0.23%
-$617.30K
TERNS PHARMACEUTICALS INC
339,533
187,062
-152,471
0.19%
-$3.86M
Magnolia Medical Technologies
37,749
1
-37,748
0.00%
-$38
▶
Unchanged
· 17 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
Kardium Inc - Series 8 Class D Preferred shares
13,234,820
13,234,820
0
0.24%
$0
Curevo Inc
2,031,087
2,031,087
0
0.10%
$0
Curevo Inc - Series B
1,348,208
1,348,208
0
0.07%
$0
Magnolia Medical Technologies
1,821,717
1,821,717
0
0.05%
-$528.30K
Element Biosciences Inc
425,023
425,023
0
0.05%
$0
Curevo Inc - Series B-1
886,774
886,774
0
0.04%
$0
PFIZER INC-CVR
390,971
390,971
0
0.04%
$0
TwinStrand Biosciences Inc
344,314
344,314
0
0.03%
$0
Freenome Holdings Inc - Series D
342,803
342,803
0
0.02%
$0
Freenome Holdings Inc - Series C
337,474
337,474
0
0.02%
$0
Sonoma Biotherapeutics Inc - Series B
1,255,200
1,255,200
0
0.02%
-$985.33K
Asher Biotherapeutics - Series C
2,580,733
2,580,733
0
0.02%
$0
Sonoma Biotherapeutics Inc - Series B-1
669,428
669,428
0
0.01%
-$525.50K
Attralus Inc
669,935
669,935
0
0.01%
$0
Asher Biotherapeutics Inc
1,214,301
1,214,301
0
0.01%
$0
NOVO NORDISK A/S - CVR
569,281
569,281
0
0.01%
$0
Magnolia Medical Technologies
301,933
301,933
0
0.01%
-$61.76K
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