Portfolio moves
Net position changes between two of this fund's N-PORT
snapshots. These are differences between point-in-time reports — not a
trade log — and share counts can be affected by splits and other corporate
actions.
Dec 31, 2025 → Mar 31, 2026
Expand a category to
see the positions behind it, ranked by weight.
▶
Opened
· 32 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
AstraZeneca PLC ORD USD0.25
0
37,129
37,129
3.23%
$7.32M
JOHNSON&JOHNSON
0
22,972
22,972
2.47%
$5.62M
AMGEN INC
0
6,637
6,637
1.03%
$2.34M
BELITE BIO INC ADR
0
4,800
4,800
0.34%
$765.31K
MODERNA INC
0
12,539
12,539
0.28%
$636.98K
ALUMIS INC
0
26,808
26,808
0.26%
$590.58K
WEST PHARMACEUTICAL SVCS INC
0
2,100
2,100
0.23%
$526.34K
ERASCA INC
0
28,600
28,600
0.20%
$462.75K
PALVELLA THERAPEUTICS INC
0
3,373
3,373
0.19%
$420.44K
CHARLES RIVER LABS INTL INC
0
2,002
2,002
0.15%
$345.34K
STOKE THERAPEUTICS INC
0
10,000
10,000
0.14%
$325.60K
TANGO THERAPEUTICS INC
0
14,300
14,300
0.13%
$299.16K
CORVUS PHARMACEUTICALS INC
0
19,845
19,845
0.13%
$290.33K
VIATRIS INC
0
20,800
20,800
0.12%
$281.01K
OCULAR THERAPEUTIX INC
0
31,800
31,800
0.12%
$269.35K
TYRA BIOSCIENCES INC
0
6,900
6,900
0.12%
$264.27K
MEDPACE HOLDINGS INC
0
500
500
0.11%
$240.10K
GENERATE BIOMEDI
0
18,234
18,234
0.10%
$227.92K
LIQUIDIA TECHNOLOGIES INC
0
5,811
5,811
0.10%
$219.31K
CULLINAN THERAPE
0
15,200
15,200
0.10%
$215.99K
LANTHEUS HOLDING
0
2,700
2,700
0.09%
$204.80K
ATRIUM THERAPEUTICS INC
0
14,900
14,900
0.09%
$199.21K
SPYGLASS PHARMA
0
5,992
5,992
0.07%
$155.25K
ALTO NEUROSCIENCE INC
0
5,900
5,900
0.06%
$132.63K
AKTIS ONCOLOGY I
0
6,809
6,809
0.05%
$121.81K
TECTONIC THERAPEUTIC INC
0
2,700
2,700
0.04%
$83.46K
EIKON THERAPEUTICS INC
0
7,211
7,211
0.03%
$76.29K
IMMIX BIOPHARMA INC
0
7,200
7,200
0.03%
$65.59K
ENLIVEN THERAPEUTICS INC
0
1,200
1,200
0.02%
$47.04K
ADLAI NORTYE LTD ADR
0
4,767
4,767
0.01%
$32.99K
TENAX THERAPEUTICS INC
0
1,202
1,202
0.01%
$19.22K
CONTRA GENERATION BIO COMMON STOCK
0
3,769
3,769
0.00%
$3.95K
▶
Exited
· 28 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
ASTRAZENECA PLC SPONS ADR
76,396
0
-76,396
0.00%
-$7.02M
PENUMBRA INC
11,098
0
-11,098
0.00%
-$3.45M
NEUROCRINE BIOSCIENCES INC
5,187
0
-5,187
0.00%
-$735.67K
WATERS CORP
1,800
0
-1,800
0.00%
-$683.69K
ARCELLX INC
9,119
0
-9,119
0.00%
-$594.56K
BIO-TECHNE CORP
8,921
0
-8,921
0.00%
-$524.64K
TEVA PHARMACEUTICAL IND ADR
16,200
0
-16,200
0.00%
-$505.60K
GENEDX HOLDINGS CORP-A
3,568
0
-3,568
0.00%
-$464.05K
ZOETIS INC CL A
3,100
0
-3,100
0.00%
-$390.04K
ARCUTIS BIOTHERAPEUTICS INC
12,700
0
-12,700
0.00%
-$368.81K
MEDLINE INC-A
7,732
0
-7,732
0.00%
-$324.74K
HEARTFLOW INC
9,934
0
-9,934
0.00%
-$289.58K
ULTRAGENYX PHARMA INC
12,318
0
-12,318
0.00%
-$283.31K
UROGEN PHARMA LTD COMMON STOCK USD.01
10,800
0
-10,800
0.00%
-$252.94K
ALKERMES PLC
8,455
0
-8,455
0.00%
-$236.57K
ELANCO ANIMAL HEALTH INC
9,000
0
-9,000
0.00%
-$203.67K
SOLENO THERAPEUTICS INC
3,326
0
-3,326
0.00%
-$153.99K
XENON PHARMACEUTICALS INC
2,900
0
-2,900
0.00%
-$129.98K
NEWAMSTERDAM PHARMA CO NV COMMON STOCK
2,900
0
-2,900
0.00%
-$101.73K
UNIQURE NV COMMON STOCK EUR.05
4,127
0
-4,127
0.00%
-$98.76K
UCB SA COMMON STOCK
329
0
-329
0.00%
-$91.67K
PALISADE BIO INC
27,162
0
-27,162
0.00%
-$63.83K
VOYAGER THERAPEUTICS INC
15,964
0
-15,964
0.00%
-$62.74K
ORCHESTRA BIOMED HOLDINGS INC
13,354
0
-13,354
0.00%
-$55.42K
PRELUDE THERAPEUTICS INC
17,428
0
-17,428
0.00%
-$50.54K
SANA BIOTECHNOLOGY INC
10,300
0
-10,300
0.00%
-$41.92K
ATAIBECKLEY INC
8,100
0
-8,100
0.00%
-$33.13K
GENERATION BIO C
3,769
0
-3,769
0.00%
-$21.41K
▶
Increased
· 50 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
THERMO FISHER SCIENTIFIC INC
18,203
19,052
849
4.12%
-$1.18M
MERCK & CO
44,300
65,688
21,388
3.48%
$3.24M
UNITEDHEALTH GRP
24,695
26,309
1,614
3.14%
-$1.03M
VERTEX PHARMACEUTICALS INC
9,444
12,528
3,084
2.46%
$1.31M
UNITED THERAPEUTICS CORP DEL
4,953
5,491
538
1.43%
$842.70K
REVOLUTION MEDICINES INC
30,724
32,474
1,750
1.39%
$710.93K
PROTAGONIST THERAPEUTICS INC
20,838
25,165
4,327
1.17%
$832.40K
ROIVANT SCIENCES
72,989
95,284
22,295
1.16%
$1.06M
SUMMIT THERAPEUTICS INC
106,991
131,177
24,186
1.10%
$615.84K
CVS HEALTH CORP
27,194
28,410
1,216
0.90%
-$117.71K
CG ONCOLOGY INC
24,016
24,056
40
0.72%
$630.97K
CARDINAL HEALTH INC
7,039
7,652
613
0.71%
$170.43K
BRIDGEBIO PHARMA INC
19,233
19,531
298
0.64%
-$20.76K
CHUGAI PHARMACEUTICAL CO LTD COMMON STOCK
23,400
25,000
1,600
0.61%
$151.11K
STRUCTURE THERAPEUTICS INC ADR
23,229
28,241
5,012
0.60%
-$254.36K
ROYALTY PHARMA PLC COMMON STOCK
16,108
27,659
11,551
0.58%
$704.39K
EDWARDS LIFESCIENCES CORP
12,478
12,785
307
0.45%
-$39.93K
Abivax SA SPONSORED ADS
9,011
9,016
5
0.44%
-$211.25K
T Rowe Price Government Reserve Investment Fund
367,787
986,092
618,305
0.43%
$618.30K
DIANTHUS THERAPEUTICS INC
4,502
11,216
6,714
0.41%
$755.72K
MADRIGAL PHARMACEUTICALS INC
1,506
1,671
165
0.39%
-$2.29K
IQVIA HOLDINGS INC
3,750
4,791
1,041
0.36%
-$28.23K
KODIAK SCIENCES INC
17,028
21,314
4,286
0.36%
$336.39K
MONTE ROSA THERAPEUTICS INC
31,809
45,126
13,317
0.33%
$243.56K
TERNS PHARMACEUTICALS INC
9,994
13,841
3,847
0.32%
$325.94K
MIRUM PHARMACEUTICALS INC
3,100
7,430
4,330
0.30%
$441.51K
ALIGNMENT HEALTHCARE INC
34,030
34,394
364
0.27%
-$66.07K
SONOVA HOLDING AG REG COMMON STOCK CHF.05
2,233
2,403
170
0.24%
-$29.69K
MBX BIOSCIENCES INC
14,724
17,761
3,037
0.23%
$65.77K
ORIC PHARMACEUTICALS INC
26,621
41,012
14,391
0.23%
$301.86K
SSC GOVERNMENT MM GVMXX /
412,594
500,000
87,406
0.22%
$87.41K
ARROWHEAD PHARMACEUTICALS INC
7,600
7,841
241
0.22%
-$12.93K
NURIX THERAPEUTICS INC
30,800
31,364
564
0.21%
-$98.13K
CARIS LIFE SCIENCES INC
22,632
26,832
4,200
0.21%
-$130.86K
ORUKA THERAPEUTICS INC
8,520
9,120
600
0.20%
$189.09K
BILLIONTOONE INC
2,903
5,603
2,700
0.19%
$204.72K
CENTENE CORP
13,214
13,351
137
0.19%
-$106.64K
BIO RAD LABS CL A
1,144
1,537
393
0.19%
$81.82K
MOONLAKE IMMUNOTHERAPEUTICS
18,575
21,385
2,810
0.18%
$153.80K
RELAY THERAPEUTICS INC
34,671
36,491
1,820
0.16%
$69.77K
Wave Life Sciences Ltd. COM NPV
37,722
47,883
10,161
0.15%
-$294.12K
COGENT BIOSCIENCES INC
7,384
7,984
600
0.14%
$45.02K
ALLOGENE THERAPEUTICS INC
81,376
125,876
44,500
0.14%
$195.65K
BIOHAVEN LTD
22,549
31,509
8,960
0.12%
$11.99K
ELIEM THERAPEUTICS INC
34,800
38,800
4,000
0.12%
$126.58K
SHATTUCK LABS INC
34,305
36,300
1,995
0.10%
$108.20K
IOVANCE BIOTHERAPEUTICS INC
31,687
66,187
34,500
0.10%
$145.81K
SENSORION SA COMMON STOCK EUR.1
182,870
326,680
143,810
0.07%
$83.02K
ENTRADA THERAPEUTICS INC
11,625
11,642
17
0.06%
$27.42K
MONOPAR THERAPEUTICS INC
364
864
500
0.02%
$23.57K
▶
Decreased
· 76 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
LILLY ELI and CO
28,314
25,208
-3,106
10.21%
-$7.24M
INTUITIVE SURGICAL INC
19,519
18,275
-1,244
3.71%
-$2.63M
STRYKER CORP
24,775
24,345
-430
3.52%
-$708.15K
ARGENX SE SPONSORED ADR
11,533
9,314
-2,219
3.00%
-$2.90M
ABBVIE INC
30,271
30,125
-146
2.89%
-$364.73K
REGENERON PHARMACEUTICALS INC
8,393
7,905
-488
2.69%
-$370.59K
GILEAD SCIENCES INC
44,553
43,100
-1,453
2.65%
$538.41K
DANAHER CORP
29,560
24,964
-4,596
2.08%
-$2.03M
ALNYLAM PHARMACEUTICALS INC
14,420
11,541
-2,879
1.68%
-$1.92M
Ascendis Pharma A/S
15,020
14,430
-590
1.45%
$97.71K
BEONE MEDICINES LTD COMMON STOCK USD.0001
140,298
124,598
-15,700
1.23%
-$434.10K
INSMED INC
27,085
15,382
-11,703
1.11%
-$2.20M
NATERA INC
12,096
12,057
-39
1.06%
-$359.79K
TENET HEALTHCARE CORP
12,583
12,442
-141
1.03%
-$152.56K
BRIGHTSPRING HEALTH SERVICES INC
54,101
54,000
-101
1.01%
$274.86K
BOSTON SCIENTIFIC CORP
41,953
34,293
-7,660
0.95%
-$1.85M
HCA HEALTHCARE INC
4,931
4,436
-495
0.92%
-$202.79K
GUARDANT HEALTH INC
23,103
22,713
-390
0.92%
-$261.74K
KYMERA THERAPEUTICS INC
26,842
22,089
-4,753
0.81%
-$248.78K
THE CIGNA GROUP
7,243
6,670
-573
0.78%
-$214.27K
ELEVANCE HEALTH INC
6,367
5,292
-1,075
0.68%
-$682.72K
KRYSTAL BIOTECH INC
7,113
5,944
-1,169
0.68%
-$218.18K
SCHOLAR ROCK HOLDING CORP
37,255
29,902
-7,353
0.65%
-$171.10K
IONIS PHARMACEUTICALS INC
22,738
19,249
-3,489
0.64%
-$353.40K
PRAXIS PRECISION MEDICINES INC
5,194
4,271
-923
0.61%
-$154.81K
CELCUITY INC
12,901
11,819
-1,082
0.59%
$62.27K
CENTESSA PHARMACEUTICALS LTD ADR
49,526
31,457
-18,069
0.55%
$10.83K
CENCORA INC
4,589
3,935
-654
0.54%
-$313.79K
VERA THERAPEUTICS INC
43,375
27,378
-15,997
0.49%
-$1.10M
NUVALENT INC-A
12,356
10,208
-2,148
0.46%
-$197.08K
APOGEE THERAPEUTICS INC
14,786
12,307
-2,479
0.46%
-$80.17K
INCYTE CORP
13,022
10,734
-2,288
0.44%
-$275.90K
SPYRE THERAPEUTICS INC
22,418
19,484
-2,934
0.43%
$248.36K
CYTOKINETICS INC
19,157
14,740
-4,417
0.43%
-$245.72K
CRINETICS PHARMACEUTICALS INC
25,383
25,378
-5
0.41%
-$259.85K
IMMUNOME INC
50,101
39,589
-10,512
0.38%
-$210.36K
AXSOME THERAPEUTICS INC
5,742
3,961
-1,781
0.29%
-$379.23K
BEAM THERAPEUTICS INC
27,477
25,010
-2,467
0.26%
-$165.67K
IDEXX LABS INC
2,828
1,028
-1,800
0.25%
-$1.34M
REVVITY INC
6,945
6,470
-475
0.25%
-$105.09K
SIONNA THERAPEUTICS INC
15,281
14,085
-1,196
0.25%
-$63.99K
MCKESSON CORP
730
608
-122
0.23%
-$72.67K
RHYTHM PHARMACEUTICALS INC
7,230
5,825
-1,405
0.22%
-$267.30K
Immunocore Holdings plc ADS
17,786
16,454
-1,332
0.22%
-$121.26K
RAPPORT THERAPEUTICS INC
15,921
15,736
-185
0.22%
$9.34K
VAXCYTE INC
11,005
7,498
-3,507
0.19%
-$72.06K
ENCOMPASS HEALTH CORP
3,960
3,941
-19
0.17%
-$39.10K
BEONE MEDICINES LTD ADR
1,932
1,214
-718
0.16%
-$226.44K
KESTRA MEDICAL T
18,799
17,599
-1,200
0.15%
-$147.80K
REPLIGEN CORP
4,623
2,923
-1,700
0.15%
-$413.14K
BICARA THERAPEUTICS INC
21,421
17,135
-4,286
0.15%
-$19.70K
OPTION
28,400
9,240
-19,160
0.15%
-$1.11M
DISC MEDICINE INC
9,263
5,239
-4,024
0.15%
-$400.59K
CELLDEX THERAPEUTICS INC
11,227
10,510
-717
0.15%
$28.45K
TARSUS PHARMACEUTICALS INC
8,928
4,510
-4,418
0.14%
-$414.65K
SARTORIUS AG VORZUG PREFERENCE
2,210
1,256
-954
0.14%
-$322.13K
REPLIMUNE GROUP INC
41,148
41,036
-112
0.14%
-$86.03K
DENALI THERAPEUTICS INC
26,925
14,063
-12,862
0.12%
-$174.52K
IDEAYA BIOSCIENCES
8,167
7,862
-305
0.12%
-$20.37K
OLEMA PHARMACEUTICALS INC
17,800
17,454
-346
0.11%
-$184.76K
PHARVARIS NV COMMON STOCK EUR.12
17,875
8,899
-8,976
0.11%
-$244.63K
PROCEPT BIOROBOTICS CORP
8,988
7,988
-1,000
0.09%
-$82.98K
VIRIDIAN THERAPEUTICS INC
16,800
8,729
-8,071
0.08%
-$352.08K
ZAI LAB LTD UNSPNRD ADR
12,926
8,626
-4,300
0.07%
-$65.76K
INSPIRE MEDICAL SYSTEMS INC
3,200
2,800
-400
0.06%
-$150.71K
AGIOS PHARMACEUTICALS INC
8,470
3,270
-5,200
0.05%
-$119.93K
BRIDGEBIO ONCOLOGY THERAPEUTIC
14,485
9,785
-4,700
0.04%
-$93.78K
ANNEXON INC
22,109
13,453
-8,656
0.03%
-$36.46K
IMMUNOVANT INC
10,631
1,800
-8,831
0.02%
-$225.53K
RADNET INC
4,301
732
-3,569
0.02%
-$265.96K
MEDIWOUND LTD COMMON STOCK ILS.01
3,687
2,287
-1,400
0.02%
-$31.22K
LENZ THERAPEUTICS INC
3,800
3,467
-333
0.01%
-$29.08K
BETA BIONICS INC
8,425
2,619
-5,806
0.01%
-$230.47K
NUVATION BIO INC
40,900
4,972
-35,928
0.01%
-$345.13K
JANUX THERAPEUTICS INC
4,213
1,511
-2,702
0.01%
-$37.14K
CABALETTA BIO INC
2,887
2,181
-706
0.00%
-$456
▶
Unchanged
· 17 positions
Security
Shares Dec 2025
Shares Mar 2026
Δ shares
End %
Δ value
MOLINA HEALTHCARE INC
2,454
2,454
0
0.14%
-$98.75K
KYVERNA THERAPEUTICS INC
32,113
32,113
0
0.12%
-$24.73K
IMMUNOCORE HOLDINGS PLC SR UNSECURED 02/30 2.5
277,000
277,000
0
0.11%
-$1.90K
XENCOR INC
13,179
13,179
0
0.07%
-$42.83K
IMMATICS NV COMMON STOCK
14,000
14,000
0
0.06%
-$9.24K
EVOMMUNE INC
5,551
5,551
0
0.06%
$32.58K
Bicycle Therapeutics PLC SPONSORED ADS
25,602
25,602
0
0.05%
-$62.47K
CRESCENT BIOPHARMA INC COMMON STOCK USD.001
5,959
5,959
0
0.05%
$38.79K
IMMUNEERING CORP
17,357
17,357
0
0.04%
-$22.74K
ROCKET PHARMACEUTICALS INC
23,535
23,535
0
0.04%
$1.65K
AURA BIOSCIENCES INC
10,426
10,426
0
0.03%
$12.93K
HIMS & HERS HEAL
2,300
2,300
0
0.02%
-$26.93K
SALUDA MEDICAL INC CDI
79,512
79,512
0
0.02%
-$29.91K
GINKGO BIOWORKS HOLDINGS INC
1,971
1,971
0
0.01%
-$4.30K
REVOLUTION MEDICINES INC WARRANTS CALL EXP 17DEC26
4,502
4,502
0
0.00%
$3.60K
GENEDX HOLDINGS CORP GENEDX HOLDINGS CORP
4,862
4,862
0
0.00%
-$192
SOMALOGIC INC WARRANTS CALL EXP 31AUG26
2,050
2,050
0
0.00%
-$81
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