HELX
Franklin Genomic Advancements ETF
Franklin Templeton ETF Trust
ETF
Expense ratio1
0.50%
Net assets2
$21.45M
Holdings2
59
Category
US Equity
2025 return3
25.91%

Investment objective & strategy

As of July 28, 2025 · prospectus

Objective. Capital appreciation.

Strategy. Under normal market conditions, the Fund invests at least 80% of its net assets in equity securities of companies that are relevant to the Funds investment theme of genomic advancements. The Fund invests predominantly in common stock. Companies relevant to the Funds investment theme of genomic advancements are those that the investment manager believes are substantially focused on and/or are expected to substantially benefit from extending and enhancing the quality of human and other life (e.g., animals) by incorporating technological and scientific developments, improvements and advancements in the field of genomics into their business, such as by offering new products or services that rely on genetic engineering, gene therapy, genome analysis, DNA sequencing, synthesis or instrumentation. These companies may include … Under normal market conditions, the Fund invests at least 80% of its net assets in equity securities of companies that are relevant to the Funds investment theme of genomic advancements. The Fund invests predominantly in common stock. Companies relevant to the Funds investment theme of genomic advancements are those that the investment manager believes are substantially focused on and/or are expected to substantially benefit from extending and enhancing the quality of human and other life (e.g., animals) by incorporating technological and scientific developments, improvements and advancements in the field of genomics into their business, such as by offering new products or services that rely on genetic engineering, gene therapy, genome analysis, DNA sequencing, synthesis or instrumentation. These companies may include those that research, develop, produce, manufacture or significantly rely on or enable bionic devices, bio-inspired computing, bioinformatics, molecular medicine and diagnostics, pharmaceuticals and agricultural applications of genomics, and related equipment, techniques and processes. In pursuing the Funds investment theme, the investment manager may invest in companies in any economic sector or of any market capitalization and may invest in companies both inside and outside of the United States, including those in developing or emerging markets. Although the Fund may invest across economic sectors, the Fund concentrates its investments in health care related industries. The Fund is a non-diversified fund, which means it generally invests a greater proportion of its assets in the securities of one or more issuers and invests overall in a smaller number of issuers than a diversified fund. In selecting companies that the investment manager believes are relevant to the Funds investment theme of genomic advancements, the investment manager seeks to identify, using its own fundamental, bottom-up research and analysis, companies positioned to capitalize on disruptive innovation in or that are enabling the further development of the genomic advancements theme in the markets in which they operate. The investment managers internal research and analysis leverages insights from diverse sources, including external research, to develop and refine its investment theme and identify and take advantage of trends that have ramifications for individual companies or entire industries. The investment manager also evaluates market segments, products, services and business models positioned to benefit significantly from advancements in genomics relative to broad securities markets, and seeks to identify the primary beneficiaries of new trends or developments in genomics to select investments for the Fund. The investment manager may seek to sell a security if: (i) the security reaches its valuation target; (ii) the security reaches its position size limit in the Funds portfolio; (iii) the securitys fundamentals deteriorate; (iv) there are adverse policy changes that could affect the securitys outlook; or (v) better investment opportunities become available.

Top holdings

As of March 31, 2026 · N-PORT
SecurityTickerValue% of fund
GUARDANT HEALTH INC $1.45M 6.77%
NATERA INC $1.43M 6.65%
KRYSTAL BIOTECH INC $1.14M 5.32%
UNITED THERAPEUTICS CORP DEL $996.21K 4.64%
INSMED INC $970.00K 4.52%
BRIDGEBIO PHARMA INC $905.38K 4.22%
LIGAND PHARMACEUTICALS $757.47K 3.53%
ASTRAZENECA PLC $728.73K 3.40%
ADAPTIVE BIOTECHNOLOGIES CORP $669.64K 3.12%
VERTEX PHARMACEUTICALS INC $640.78K 2.99%
View all holdings →

Allocation by sector

As of March 31, 2026 · N-PORT
View portfolio breakdown →

Portfolio moves

Dec 31, 2025 → Mar 31, 2026
Opened
4
Exited
6
Increased
49
Decreased
6
Unchanged
2

How many positions this fund opened, exited, grew, trimmed, or left unchanged between its two most recent N-PORT snapshots — net changes between point-in-time reports, not a trade log.

View portfolio moves →

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FundOverlapNet exp.
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Biotechnology Fund 34% 1.74%
WisdomTree BioRevolution Fund · WDNA 30% 0.45%
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Advisers

As of March 31, 2025 · N-CEN
FirmRole
Franklin Advisers, Inc. Adviser

Footnotes

  1. Expense ratio as of July 28, 2025, from the fund's prospectus.
  2. Net assets and holdings count as of March 31, 2026, from the fund's N-PORT filing.
  3. Total return for calendar year 2025, before tax and after fund expenses. Computed by compounding the twelve monthly total returns the fund reported in its SEC N-PORT filings for 2025 (the latest prospectus does not yet chart this year).

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