Portfolio concentration
As of February 28, 2026 · N-PORT
Holdings
187
Top-10 weight
53.26%
Effective holdings
?
The number of equal-weight positions that would produce this portfolio's concentration (1 ÷ Herfindahl index). A 500-stock fund dominated by a few mega-caps might have only ~100 effective holdings.
22
Crowding
?
The value-weighted average number of funds that also own this fund's positions. High = consensus/crowded picks; low = holdings few other funds own.
768.6
Holdings
As of February 28, 2026 · N-PORT| # | Security | Ticker | Shares | Value | % of fund |
|---|---|---|---|---|---|
| 1 | ABBVIE INC | — | 3,049,432 | $707.71M | 13.22% |
| 2 | KRYSTAL BIOTECH INC | — | 1,806,522 | $497.95M | 9.30% |
| 3 | GILEAD SCIENCES INC | — | 3,149,952 | $469.19M | 8.77% |
| 4 | AMGEN INC | — | 1,149,551 | $446.21M | 8.34% |
| 5 | ALNYLAM PHARMACEUTICALS INC | — | 496,683 | $165.36M | 3.09% |
| 6 | Fidelity Securities Lending Cash Central Fund | — | 136,216,589 | $136.23M | 2.55% |
| 7 | PRAXIS PRECISION MEDICINES INC | — | 390,500 | $131.50M | 2.46% |
| 8 | Ascendis Pharma A/S | — | 558,201 | $130.34M | 2.44% |
| 9 | INSMED INC | — | 811,101 | $121.12M | 2.26% |
| 10 | UCB SA | — | 390,274 | $116.35M | 2.17% |
| 11 | ARGENX SE SPONSORED ADR | — | 149,344 | $114.53M | 2.14% |
| 12 | REGENERON PHARMACEUTICALS INC | — | 101,316 | $79.20M | 1.48% |
| 13 | MODERNA INC | — | 1,432,529 | $76.74M | 1.43% |
| 14 | SCHOLAR ROCK HOLDING CORP | — | 1,650,449 | $73.07M | 1.37% |
| 15 | NATERA INC | — | 331,532 | $68.97M | 1.29% |
| 16 | COGENT BIOSCIENCES INC | — | 1,691,394 | $65.71M | 1.23% |
| 17 | CENTESSA PHARMACEUTICALS LTD ADR | — | 2,187,494 | $58.76M | 1.10% |
| 18 | BIOGEN INC | — | 299,435 | $57.44M | 1.07% |
| 19 | ROIVANT SCIENCES LTD | — | 1,972,719 | $57.09M | 1.07% |
| 20 | VERTEX PHARMACEUTICALS INC | — | 112,900 | $56.09M | 1.05% |
| 21 | BRIDGEBIO PHARMA INC | — | 707,304 | $47.02M | 0.88% |
| 22 | PROTAGONIST THERAPEUTICS INC | — | 506,713 | $46.66M | 0.87% |
| 23 | IMMUNOME INC | — | 2,131,664 | $46.60M | 0.87% |
| 24 | TERNS PHARMACEUTICALS INC | — | 1,079,186 | $45.46M | 0.85% |
| 25 | REVOLUTION MEDICINES INC | — | 438,772 | $44.76M | 0.84% |
| 26 | KYMERA THERAPEUTICS INC | — | 462,441 | $42.24M | 0.79% |
| 27 | IONIS PHARMACEUTICALS INC | — | 476,377 | $38.66M | 0.72% |
| 28 | ARRIVENT BIOPHARMA INC | — | 1,680,003 | $38.59M | 0.72% |
| 29 | CRINETICS PHARMACEUTICALS INC | — | 926,671 | $38.09M | 0.71% |
| 30 | Abivax SA SPONSORED ADS | ABVX US | 301,600 | $36.58M | 0.68% |
| 31 | STRUCTURE THERAPEUTICS INC ADR | — | 564,438 | $35.55M | 0.66% |
| 32 | DISC MEDICINE INC | — | 532,174 | $35.45M | 0.66% |
| 33 | GALDERMA GROUP A | — | 184,660 | $34.85M | 0.65% |
| 34 | ZEALAND PHARMA A | — | 589,130 | $33.89M | 0.63% |
| 35 | CYTOKINETICS INC | — | 503,175 | $31.31M | 0.59% |
| 36 | CANDEL THERAPEUTICS INC | — | 5,911,951 | $31.04M | 0.58% |
| 37 | VIRIDIAN THERAPEUTICS INC | — | 1,001,204 | $29.42M | 0.55% |
| 38 | VAXCYTE INC | — | 470,455 | $29.05M | 0.54% |
| 39 | STOKE THERAPEUTICS INC | — | 792,594 | $28.86M | 0.54% |
| 40 | NUVALENT INC-A | — | 273,399 | $27.87M | 0.52% |
| 41 | APOGEE THERAPEUTICS INC | — | 392,757 | $27.49M | 0.51% |
| 42 | TREVI THERAPEUTICS INC | — | 2,288,485 | $27.28M | 0.51% |
| 43 | ANNEXON INC | — | 4,733,596 | $26.51M | 0.50% |
| 44 | ARROWHEAD PHARMACEUTICALS INC | — | 409,378 | $25.90M | 0.48% |
| 45 | DIANTHUS THERAPEUTICS INC | — | 432,218 | $23.85M | 0.45% |
| 46 | VOR BIOPHARMA INC | — | 1,536,125 | $23.72M | 0.44% |
| 47 | EDGEWISE THERAPEUTICS INC | — | 776,925 | $23.65M | 0.44% |
| 48 | UNITED THERAPEUTICS CORP DEL | — | 44,593 | $22.47M | 0.42% |
| 49 | INTELLIA THERAPEUTICS INC | — | 1,607,833 | $22.16M | 0.41% |
| 50 | TRAVERE THERAPEUTICS INC | — | 720,343 | $21.46M | 0.40% |
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