# Portfolio overlap — LABU vs PRHSX

Comparing **Direxion Daily S&P Biotech Bull 3X Shares** (2026-04-30) and **T. Rowe Price Health Sciences Fund, Inc.** (2026-03-31).

- Shared positions: 66
- Direxion Daily S&P Biotech Bull 3X Shares covered by T. Rowe Price Health Sciences Fund, Inc.: 0.2407397883133706346338953085
- T. Rowe Price Health Sciences Fund, Inc. covered by Direxion Daily S&P Biotech Bull 3X Shares: 0.2407397883133706346338953083

## Direxion Daily S&P Biotech Bull 3X Shares — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| DREYFUS GOVT CASH MGMT FUND | 0.074333 |  |
| US ULTRA BOND CBT Sep25 | 0.072638 |  |
| GOLDMAN FINL SQ TRSRY INST 506 | 0.062671 |  |
| GOLDMAN SACHS FIN GOV 465 INSTITUT | 0.017087 |  |
| APELLIS PHARMACEUTICALS INC | 0.014425 |  |
| REVOLUTION MEDICINES INC | 0.012740 | ✓ |
| TRAVERE THERAPEUTICS INC | 0.012532 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.011134 | ✓ |
| TWIST BIOSCIENCE CORP | 0.010981 |  |
| SUMMIT THERAPEUTICS INC | 0.010852 | ✓ |
| ALKERMES PLC | 0.010687 |  |
| TG THERAPEUTICS INC | 0.010602 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.010554 | ✓ |
| BEAM THERAPEUTICS INC | 0.010239 | ✓ |
| APOGEE THERAPEUTICS INC | 0.009771 | ✓ |
| SCHOLAR ROCK HOLDING CORP | 0.009503 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.009450 | ✓ |
| EXELIXIS INC | 0.009375 |  |
| MIRUM PHARMACEUTICALS INC | 0.009338 | ✓ |
| UNITED THERAPEUTICS CORP DEL | 0.009236 | ✓ |
| NATERA INC | 0.009233 | ✓ |
| CELCUITY INC | 0.009229 | ✓ |
| CRISPR Therapeutics A.G. Series A | 0.009229 |  |
| KRYSTAL BIOTECH INC | 0.009054 | ✓ |
| PROTAGONIST THERAPEUTICS INC | 0.009031 | ✓ |
| NEUROCRINE BIOSCIENCES INC | 0.008948 |  |
| INCYTE CORP | 0.008861 | ✓ |
| CG ONCOLOGY INC | 0.008856 | ✓ |
| CYTOKINETICS INC | 0.008851 | ✓ |
| NUVALENT INC-A | 0.008823 | ✓ |
| IONIS PHARMACEUTICALS INC | 0.008800 | ✓ |
| BRIDGEBIO PHARMA INC | 0.008769 | ✓ |
| VAXCYTE INC | 0.008759 | ✓ |
| KYMERA THERAPEUTICS INC | 0.008755 | ✓ |
| BIOGEN INC | 0.008747 |  |
| COGENT BIOSCIENCES INC | 0.008733 | ✓ |
| PTC THERAPEUTICS INC | 0.008722 |  |
| INSMED INC | 0.008611 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.008503 | ✓ |
| ROIVANT SCIENCES | 0.008491 |  |
| HALOZYME THERAPEUTICS INC | 0.008430 |  |
| ARCUTIS BIOTHERAPEUTICS INC | 0.008295 |  |
| SPYRE THERAPEUTICS INC | 0.008272 | ✓ |
| SOLENO THERAPEUTICS INC | 0.008209 |  |
| ABBVIE INC | 0.008171 | ✓ |
| AMGEN INC | 0.008070 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.008035 | ✓ |
| ULTRAGENYX PHARMA INC | 0.007972 |  |
| ACADIA PHARMACEUTICALS INC | 0.007961 |  |
| RHYTHM PHARMACEUTICALS INC | 0.007957 | ✓ |

## T. Rowe Price Health Sciences Fund, Inc. — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| LILLY ELI and CO | 0.101410 |  |
| THERMO FISHER SCIENTIFIC INC | 0.040674 |  |
| INTUITIVE SURGICAL INC | 0.036548 |  |
| STRYKER CORP | 0.034631 |  |
| MERCK & CO | 0.034429 |  |
| ASTRAZENECA PLC | 0.031721 |  |
| UNITEDHEALTH GRP | 0.030888 |  |
| ARGENX SE SPONSORED ADR | 0.029196 |  |
| ABBVIE INC | 0.028431 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.026485 | ✓ |
| GILEAD SCIENCES INC | 0.026046 | ✓ |
| JOHNSON&JOHNSON | 0.024434 |  |
| VERTEX PHARMACEUTICALS INC | 0.024250 | ✓ |
| DANAHER CORP | 0.020469 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.016163 | ✓ |
| Ascendis Pharma A/S | 0.014205 |  |
| REVOLUTION MEDICINES INC | 0.013574 | ✓ |
| UNITED THERAPEUTICS CORP DEL | 0.013449 | ✓ |
| BEONE MEDICINE-H | 0.011863 |  |
| ROIVANT SCIENCES LTD | 0.011315 |  |
| PROTAGONIST THERAPEUTICS INC | 0.011055 | ✓ |
| INSMED INC | 0.010553 | ✓ |
| SUMMIT THERAPEUTICS INC | 0.010358 | ✓ |
| NATERA INC | 0.010318 | ✓ |
| TENET HEALTHCARE CORP | 0.010054 |  |
| BRIGHTSPRING HEALTH SERVICES INC | 0.009839 |  |
| AMGEN INC | 0.009815 | ✓ |
| BOSTON SCIENTIFIC CORP | 0.009243 |  |
| HCA HEALTHCARE INC | 0.008963 |  |
| GUARDANT HEALTH INC | 0.008959 |  |
| CVS HEALTH CORP | 0.008643 |  |
| KYMERA THERAPEUTICS INC | 0.007668 | ✓ |
| THE CIGNA GROUP | 0.007357 |  |
| CG ONCOLOGY INC | 0.006891 | ✓ |
| CARDINAL HEALTH INC | 0.006758 |  |
| ELEVANCE HEALTH INC | 0.006568 |  |
| KRYSTAL BIOTECH INC | 0.006488 | ✓ |
| SCHOLAR ROCK HOLDING CORP | 0.006185 | ✓ |
| IONIS PHARMACEUTICALS INC | 0.006088 | ✓ |
| BRIDGEBIO PHARMA INC | 0.005894 | ✓ |
| CHUGAI PHARMA CO | 0.005779 |  |
| STRUCTURE THERAPEUTICS INC ADR | 0.005636 |  |
| PRAXIS PRECISION MEDICINES INC | 0.005602 | ✓ |
| CELCUITY INC | 0.005566 | ✓ |
| ROYALTY PHARMA PLC | 0.005471 |  |
| CENCORA INC | 0.005185 |  |
| CENTESSA PHARMACEUTICALS LTD ADR | 0.004989 |  |
| VERA THERAPEUTICS INC | 0.004566 | ✓ |
| NUVALENT INC-A | 0.004326 | ✓ |
| APOGEE THERAPEUTICS INC | 0.004291 | ✓ |


## Sources

- N-PORT (fund A) — accession `0001193125-26-287439` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1424958/000119312526287439/0001193125-26-287439-index.htm>
- N-PORT (fund B) — accession `0001099263-26-006598` (as of 2026-03-31)
  <https://www.sec.gov/Archives/edgar/data/1002624/000109926326006598/0001099263-26-006598-index.htm>

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