# Portfolio overlap — LABU vs BBC

Comparing **Direxion Daily S&P Biotech Bull 3X Shares** (2026-04-30) and **Virtus LifeSci Biotech Clinical Trials ETF** (2026-04-30).

- Shared positions: 77
- Direxion Daily S&P Biotech Bull 3X Shares covered by Virtus LifeSci Biotech Clinical Trials ETF: 0.3452660813497938665634136956
- Virtus LifeSci Biotech Clinical Trials ETF covered by Direxion Daily S&P Biotech Bull 3X Shares: 0.3452660813497938665634136957

## Direxion Daily S&P Biotech Bull 3X Shares — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| DREYFUS GOVT CASH MGMT FUND | 0.074333 | ✓ |
| US ULTRA BOND CBT Sep25 | 0.072638 |  |
| GOLDMAN FINL SQ TRSRY INST 506 | 0.062671 |  |
| GOLDMAN SACHS FIN GOV 465 INSTITUT | 0.017087 |  |
| APELLIS PHARMACEUTICALS INC | 0.014425 |  |
| REVOLUTION MEDICINES INC | 0.012740 | ✓ |
| TRAVERE THERAPEUTICS INC | 0.012532 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.011134 |  |
| TWIST BIOSCIENCE CORP | 0.010981 |  |
| SUMMIT THERAPEUTICS INC | 0.010852 | ✓ |
| ALKERMES PLC | 0.010687 |  |
| TG THERAPEUTICS INC | 0.010602 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.010554 |  |
| BEAM THERAPEUTICS INC | 0.010239 | ✓ |
| APOGEE THERAPEUTICS INC | 0.009771 | ✓ |
| SCHOLAR ROCK HOLDING CORP | 0.009503 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.009450 | ✓ |
| EXELIXIS INC | 0.009375 |  |
| MIRUM PHARMACEUTICALS INC | 0.009338 |  |
| UNITED THERAPEUTICS CORP DEL | 0.009236 |  |
| NATERA INC | 0.009233 |  |
| CELCUITY INC | 0.009229 | ✓ |
| CRISPR Therapeutics A.G. Series A | 0.009229 |  |
| KRYSTAL BIOTECH INC | 0.009054 |  |
| PROTAGONIST THERAPEUTICS INC | 0.009031 | ✓ |
| NEUROCRINE BIOSCIENCES INC | 0.008948 |  |
| INCYTE CORP | 0.008861 |  |
| CG ONCOLOGY INC | 0.008856 | ✓ |
| CYTOKINETICS INC | 0.008851 | ✓ |
| NUVALENT INC-A | 0.008823 | ✓ |
| IONIS PHARMACEUTICALS INC | 0.008800 |  |
| BRIDGEBIO PHARMA INC | 0.008769 |  |
| VAXCYTE INC | 0.008759 | ✓ |
| KYMERA THERAPEUTICS INC | 0.008755 | ✓ |
| BIOGEN INC | 0.008747 |  |
| COGENT BIOSCIENCES INC | 0.008733 | ✓ |
| PTC THERAPEUTICS INC | 0.008722 |  |
| INSMED INC | 0.008611 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.008503 |  |
| ROIVANT SCIENCES | 0.008491 |  |
| HALOZYME THERAPEUTICS INC | 0.008430 |  |
| ARCUTIS BIOTHERAPEUTICS INC | 0.008295 |  |
| SPYRE THERAPEUTICS INC | 0.008272 | ✓ |
| SOLENO THERAPEUTICS INC | 0.008209 | ✓ |
| ABBVIE INC | 0.008171 |  |
| AMGEN INC | 0.008070 |  |
| REGENERON PHARMACEUTICALS INC | 0.008035 |  |
| ULTRAGENYX PHARMA INC | 0.007972 |  |
| ACADIA PHARMACEUTICALS INC | 0.007961 |  |
| RHYTHM PHARMACEUTICALS INC | 0.007957 |  |

## Virtus LifeSci Biotech Clinical Trials ETF — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| DREYFUS GOVT CASH MGMT FUND | 0.022336 | ✓ |
| ERASCA INC | 0.021401 | ✓ |
| ENLIVEN THERAPEUTICS INC | 0.017690 |  |
| TANGO THERAPEUTICS INC | 0.016727 | ✓ |
| ORUKA THERAPEUTICS INC | 0.016394 | ✓ |
| SPYRE THERAPEUTICS INC | 0.016016 | ✓ |
| ALUMIS INC | 0.015544 |  |
| DIANTHUS THERAPEUTICS INC | 0.015075 | ✓ |
| KODIAK SCIENCES INC | 0.013209 | ✓ |
| REVOLUTION MEDICINES INC | 0.013206 | ✓ |
| CORVUS PHARMACEUTICALS INC | 0.013129 | ✓ |
| REZOLUTE INC | 0.012861 |  |
| DEFINIUM THERAPEUTICS INC | 0.012612 |  |
| CG ONCOLOGY INC | 0.011792 | ✓ |
| JADE BIOSCIENCES INC | 0.011783 |  |
| INHIBRX BIOSCIENCES INC | 0.011741 | ✓ |
| RELAY THERAPEUTICS INC | 0.011675 | ✓ |
| GH RESEARCH PLC | 0.011394 |  |
| NEKTAR THERAPEUTICS | 0.011245 |  |
| TYRA BIOSCIENCES INC | 0.011108 | ✓ |
| VIR BIOTECHNOLOGY INC | 0.011046 | ✓ |
| INTELLIA THERAPEUTICS INC | 0.010811 | ✓ |
| CENTESSA PHARMACEUTICALS LTD ADR | 0.010757 |  |
| ANAPTYSBIO INC | 0.010576 | ✓ |
| OMEROS CORP | 0.010405 |  |
| TECTONIC THERAPEUTIC INC | 0.010238 |  |
| ALLOGENE THERAPEUTICS INC | 0.010205 | ✓ |
| COMPASS Pathways PLC, ADR | 0.009724 |  |
| EDGEWISE THERAPEUTICS INC | 0.009482 |  |
| PALVELLA THERAPEUTICS INC | 0.009410 | ✓ |
| CAPRICOR THERAPEUTICS INC | 0.009335 | ✓ |
| VAXCYTE INC | 0.009303 | ✓ |
| PHARVARIS NV | 0.009285 |  |
| ARRIVENT BIOPHARMA INC | 0.009208 | ✓ |
| XENON PHARMACEUTICALS INC | 0.009201 |  |
| NEUROGENE INC | 0.009022 |  |
| SUMMIT THERAPEUTICS INC | 0.008835 | ✓ |
| AMYLYX PHARMACEUTICALS INC | 0.008835 |  |
| CELLDEX THERAPEUTICS INC | 0.008645 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.008574 | ✓ |
| ARCUS BIOSCIENCES INC | 0.008568 | ✓ |
| ANNEXON INC | 0.008544 | ✓ |
| TERNS PHARMACEUTICALS INC | 0.008507 |  |
| LIQUIDIA TECHNOLOGIES INC | 0.008497 |  |
| MONTE ROSA THERAPEUTICS INC | 0.008493 | ✓ |
| IMMUNOME INC | 0.008479 | ✓ |
| BICARA THERAPEUTICS INC | 0.008447 | ✓ |
| CELCUITY INC | 0.008336 | ✓ |
| IRONWOOD PHARMA CL A (PEND) | 0.008335 | ✓ |
| AbCellera Biologics Inc COM | 0.008293 |  |


## Sources

- N-PORT (fund A) — accession `0001193125-26-287439` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1424958/000119312526287439/0001193125-26-287439-index.htm>
- N-PORT (fund B) — accession `0000940400-26-024966` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1559109/000094040026024966/0000940400-26-024966-index.htm>

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