# Portfolio overlap — IBBQ vs LABU

Comparing **Invesco Nasdaq Biotechnology ETF** (2026-02-28) and **Direxion Daily S&P Biotech Bull 3X Shares** (2026-04-30).

- Shared positions: 117
- Invesco Nasdaq Biotechnology ETF covered by Direxion Daily S&P Biotech Bull 3X Shares: 0.3112632142313287066429172239
- Direxion Daily S&P Biotech Bull 3X Shares covered by Invesco Nasdaq Biotechnology ETF: 0.3112632142313287066429172241

## Invesco Nasdaq Biotechnology ETF — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| Invesco Private Prime Fund | 0.119343 |  |
| GILEAD SCIENCES INC | 0.080238 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.077654 | ✓ |
| AMGEN INC | 0.076151 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.050316 | ✓ |
| Invesco Private Government Fund | 0.046317 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.027416 | ✓ |
| INSMED INC | 0.019862 | ✓ |
| BIOGEN INC | 0.017541 | ✓ |
| ARGENX SE SPONSORED ADR | 0.013933 |  |
| UNITED THERAPEUTICS CORP DEL | 0.013538 | ✓ |
| MODERNA INC | 0.013057 | ✓ |
| ILLUMINA INC | 0.012816 |  |
| ROIVANT SCIENCES | 0.012560 | ✓ |
| INCYTE CORP | 0.012409 | ✓ |
| ROYALTY PHARMA-A | 0.012313 |  |
| REVOLUTION MEDICINES INC | 0.012302 | ✓ |
| VIATRIS INC | 0.010728 |  |
| Ascendis Pharma A/S | 0.008942 |  |
| NEUROCRINE BIOSCIENCES INC | 0.008224 | ✓ |
| IONIS PHARMACEUTICALS INC | 0.008197 | ✓ |
| SANOFI SPON ADR | 0.008040 |  |
| BRIDGEBIO PHARMA INC | 0.008002 | ✓ |
| MEDPACE HOLDINGS INC | 0.007933 |  |
| SUMMIT THERAPEUTICS INC | 0.007713 | ✓ |
| GUARDANT HEALTH INC | 0.007576 |  |
| BIOMARIN PHARMACEUTICAL INC | 0.007407 | ✓ |
| EXELIXIS INC | 0.007371 | ✓ |
| JAZZ PHARMACEUTI | 0.007210 |  |
| BIONTECH SE ADR | 0.006958 |  |
| BEONE MEDICINES LTD ADR | 0.006234 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.006129 | ✓ |
| IMMUNITYBIO INC | 0.006025 | ✓ |
| TEMPUS AI INC-A | 0.005758 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.005354 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.005272 | ✓ |
| AXSOME THERAPEUTICS INC | 0.005147 |  |
| HALOZYME THERAPEUTICS INC | 0.005113 | ✓ |
| VAXCYTE INC | 0.005054 | ✓ |
| KRYSTAL BIOTECH INC | 0.005002 | ✓ |
| CYTOKINETICS INC | 0.004722 | ✓ |
| NUVALENT INC-A | 0.004609 | ✓ |
| Abivax SA SPONSORED ADS | 0.004462 |  |
| ARCELLX INC | 0.004109 |  |
| KYMERA THERAPEUTICS INC | 0.004096 | ✓ |
| RHYTHM PHARMACEUTICALS INC | 0.003858 | ✓ |
| COGENT BIOSCIENCES INC | 0.003742 | ✓ |
| PROTAGONIST THERAPEUTICS INC | 0.003614 | ✓ |
| CRISPR Therapeutics A.G. Series A | 0.003591 | ✓ |
| CARIS LIFE SCIENCES INC | 0.003520 |  |

## Direxion Daily S&P Biotech Bull 3X Shares — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| DREYFUS GOVT CASH MGMT FUND | 0.074333 |  |
| US ULTRA BOND CBT Sep25 | 0.072638 |  |
| GOLDMAN FINL SQ TRSRY INST 506 | 0.062671 |  |
| GOLDMAN SACHS FIN GOV 465 INSTITUT | 0.017087 |  |
| APELLIS PHARMACEUTICALS INC | 0.014425 | ✓ |
| REVOLUTION MEDICINES INC | 0.012740 | ✓ |
| TRAVERE THERAPEUTICS INC | 0.012532 | ✓ |
| ARROWHEAD PHARMACEUTICALS INC | 0.011134 | ✓ |
| TWIST BIOSCIENCE CORP | 0.010981 | ✓ |
| SUMMIT THERAPEUTICS INC | 0.010852 | ✓ |
| ALKERMES PLC | 0.010687 | ✓ |
| TG THERAPEUTICS INC | 0.010602 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.010554 | ✓ |
| BEAM THERAPEUTICS INC | 0.010239 | ✓ |
| APOGEE THERAPEUTICS INC | 0.009771 | ✓ |
| SCHOLAR ROCK HOLDING CORP | 0.009503 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.009450 | ✓ |
| EXELIXIS INC | 0.009375 | ✓ |
| MIRUM PHARMACEUTICALS INC | 0.009338 | ✓ |
| UNITED THERAPEUTICS CORP DEL | 0.009236 | ✓ |
| NATERA INC | 0.009233 |  |
| CELCUITY INC | 0.009229 |  |
| CRISPR Therapeutics A.G. Series A | 0.009229 | ✓ |
| KRYSTAL BIOTECH INC | 0.009054 | ✓ |
| PROTAGONIST THERAPEUTICS INC | 0.009031 | ✓ |
| NEUROCRINE BIOSCIENCES INC | 0.008948 | ✓ |
| INCYTE CORP | 0.008861 | ✓ |
| CG ONCOLOGY INC | 0.008856 | ✓ |
| CYTOKINETICS INC | 0.008851 | ✓ |
| NUVALENT INC-A | 0.008823 | ✓ |
| IONIS PHARMACEUTICALS INC | 0.008800 | ✓ |
| BRIDGEBIO PHARMA INC | 0.008769 | ✓ |
| VAXCYTE INC | 0.008759 | ✓ |
| KYMERA THERAPEUTICS INC | 0.008755 | ✓ |
| BIOGEN INC | 0.008747 | ✓ |
| COGENT BIOSCIENCES INC | 0.008733 | ✓ |
| PTC THERAPEUTICS INC | 0.008722 | ✓ |
| INSMED INC | 0.008611 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.008503 | ✓ |
| ROIVANT SCIENCES | 0.008491 | ✓ |
| HALOZYME THERAPEUTICS INC | 0.008430 | ✓ |
| ARCUTIS BIOTHERAPEUTICS INC | 0.008295 | ✓ |
| SPYRE THERAPEUTICS INC | 0.008272 | ✓ |
| SOLENO THERAPEUTICS INC | 0.008209 |  |
| ABBVIE INC | 0.008171 |  |
| AMGEN INC | 0.008070 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.008035 | ✓ |
| ULTRAGENYX PHARMA INC | 0.007972 | ✓ |
| ACADIA PHARMACEUTICALS INC | 0.007961 | ✓ |
| RHYTHM PHARMACEUTICALS INC | 0.007957 | ✓ |


## Sources

- N-PORT (fund A) — accession `0001378872-26-000841` (as of 2026-02-28)
  <https://www.sec.gov/Archives/edgar/data/1378872/000137887226000841/0001378872-26-000841-index.htm>
- N-PORT (fund B) — accession `0001193125-26-287439` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1424958/000119312526287439/0001193125-26-287439-index.htm>

---

_Informational only — not investment advice. FundWatcher presents publicly available data and makes no recommendation to buy or sell any security. Verify all figures against the source filing before relying on them._

_Data sourced from U.S. SEC EDGAR filings (Forms N-PORT, N-CEN, and prospectus Risk/Return summaries). FundWatcher is not affiliated with the SEC._

_Use of this data is subject to the FundWatcher Terms of Service. Information may be used only for personal, non-commercial research and may not be redistributed. See <https://fundwatcher.app/terms/>_