# Portfolio overlap — FBTIX vs IBB

Comparing **Fidelity Advisor Biotechnology Fund** (2026-01-31) and **iShares Biotechnology ETF** (2026-03-31).

- Shared positions: 50
- Fidelity Advisor Biotechnology Fund covered by iShares Biotechnology ETF: 0.3422533752517120364475233675
- iShares Biotechnology ETF covered by Fidelity Advisor Biotechnology Fund: 0.3422533752517120364475233675

## Fidelity Advisor Biotechnology Fund — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| ABBVIE INC | 0.160449 |  |
| GILEAD SCIENCES INC | 0.063508 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.048517 | ✓ |
| Ascendis Pharma A/S | 0.043387 | ✓ |
| COGENT BIOSCIENCES INC | 0.036970 | ✓ |
| ARGENX SE SPONSORED ADR | 0.035249 | ✓ |
| Fidelity Securities Lending Cash Central Fund | 0.034661 |  |
| INSMED INC | 0.033487 | ✓ |
| VIRIDIAN THERAPEUTICS INC | 0.030455 |  |
| BIOGEN INC | 0.027392 | ✓ |
| AMGEN INC | 0.026676 | ✓ |
| VAXCYTE INC | 0.022087 | ✓ |
| STRUCTURE THERAPEUTICS INC ADR | 0.022037 | ✓ |
| NUVALENT INC-A | 0.021962 | ✓ |
| DIANTHUS THERAPEUTICS INC | 0.020181 |  |
| AMYLYX PHARMACEUTICALS INC | 0.018003 | ✓ |
| MODERNA INC | 0.015386 | ✓ |
| APOGEE THERAPEUTICS INC | 0.015353 | ✓ |
| XENON PHARMACEUTICALS INC | 0.015092 | ✓ |
| CRINETICS PHARMACEUTICALS INC | 0.014078 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.014047 | ✓ |
| SCHOLAR ROCK HOLDING CORP | 0.013370 | ✓ |
| ORUKA THERAPEUTICS INC | 0.012597 | ✓ |
| SPYRE THERAPEUTICS INC | 0.012408 | ✓ |
| UCB SA | 0.011881 |  |
| UNIQURE N.V. | 0.011665 | ✓ |
| UPSTREAM BIO INC | 0.011120 | ✓ |
| ROIVANT SCIENCES LTD | 0.010928 | ✓ |
| NATERA INC | 0.010699 | ✓ |
| OLEMA PHARMACEUTICALS INC | 0.010424 | ✓ |
| VIKING THERAPEUTICS INC | 0.009734 |  |
| NEWAMSTERDAM PHARMA COMPANY NV | 0.009448 | ✓ |
| CYTOKINETICS INC | 0.009261 | ✓ |
| KYMERA THERAPEUTICS INC | 0.008720 | ✓ |
| JADE BIOSCIENCES INC | 0.007228 |  |
| CG ONCOLOGY INC | 0.006708 | ✓ |
| RHYTHM PHARMACEUTICALS INC | 0.006699 | ✓ |
| ENLIVEN THERAPEUTICS INC | 0.006495 | ✓ |
| ZENAS BIOPHARMA INC | 0.005986 | ✓ |
| DISC MEDICINE INC | 0.005698 | ✓ |
| ARCELLX INC | 0.005054 | ✓ |
| STOKE THERAPEUTICS INC | 0.004991 | ✓ |
| SONOMA BIOTHERAPEUTICS INC SER B PFD PP | 0.004888 |  |
| TRAVERE THERAPEUTICS INC | 0.004848 | ✓ |
| MINERALYS THERAPEUTICS INC | 0.004267 | ✓ |
| CYTOMX THERAPEUTICS INC | 0.003978 | ✓ |
| ANAPTYSBIO INC | 0.003643 | ✓ |
| SOLENO THERAPEUTICS INC | 0.003614 |  |
| CELLDEX THERAPEUTICS INC | 0.003511 |  |
| REZOLUTE INC | 0.003433 |  |

## iShares Biotechnology ETF — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| BlackRock Cash Funds: Institutional, SL Agency Shares | 0.088091 |  |
| GILEAD SCIENCES INC | 0.070642 | ✓ |
| AMGEN INC | 0.068448 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.067866 |  |
| REGENERON PHARMACEUTICALS INC | 0.065757 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.036382 | ✓ |
| INSMED INC | 0.029144 | ✓ |
| ARGENX SE SPONSORED ADR | 0.028023 | ✓ |
| BIOGEN INC | 0.022451 | ✓ |
| NATERA INC | 0.022013 | ✓ |
| UNITED THERAPEUTICS CORP DEL | 0.021000 |  |
| BEONE MEDICINES LTD ADR | 0.017638 |  |
| INCYTE CORP | 0.015508 |  |
| MODERNA INC | 0.015352 | ✓ |
| ILLUMINA INC | 0.015320 |  |
| REVOLUTION MEDICINES INC | 0.014015 |  |
| ROIVANT SCIENCES LTD | 0.011325 | ✓ |
| NEUROCRINE BIOSCIENCES INC | 0.010758 |  |
| GENMAB A/S -SP ADR DEPOSITARY RECEIPT | 0.010706 |  |
| BRIDGEBIO PHARMA INC | 0.010325 |  |
| IONIS PHARMACEUTICALS INC | 0.010161 |  |
| MEDPACE HOLDINGS INC | 0.009159 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.009127 |  |
| EXELIXIS INC | 0.009009 |  |
| BIOMARIN PHARMACEUTICAL INC | 0.008955 |  |
| Ascendis Pharma A/S | 0.008728 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.007056 | ✓ |
| CHARLES RIVER LABS INTL INC | 0.007012 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.006863 |  |
| VAXCYTE INC | 0.006821 | ✓ |
| BIO-TECHNE CORP | 0.006757 |  |
| CYTOKINETICS INC | 0.006636 | ✓ |
| HALOZYME THERAPEUTICS INC | 0.006300 |  |
| AXSOME THERAPEUTICS INC | 0.006054 |  |
| BIONTECH SE ADR | 0.005981 |  |
| KRYSTAL BIOTECH INC | 0.005479 |  |
| PROTAGONIST THERAPEUTICS INC | 0.005289 |  |
| REPLIGEN CORP | 0.005249 |  |
| KYMERA THERAPEUTICS INC | 0.004874 | ✓ |
| ALKERMES PLC | 0.004829 |  |
| RHYTHM PHARMACEUTICALS INC | 0.004632 | ✓ |
| Abivax SA SPONSORED ADS | 0.004593 |  |
| PTC THERAPEUTICS INC | 0.004536 |  |
| COGENT BIOSCIENCES INC | 0.004361 | ✓ |
| ARCELLX INC | 0.004328 | ✓ |
| TERNS PHARMACEUTICALS INC | 0.004224 |  |
| NUVALENT INC-A | 0.004088 | ✓ |
| MIRUM PHARMACEUTICALS INC | 0.004072 |  |
| TEMPUS AI INC-A | 0.003928 |  |
| XENON PHARMACEUTICALS INC | 0.003906 | ✓ |


## Sources

- N-PORT (fund A) — accession `0000035402-26-001936` (as of 2026-01-31)
  <https://www.sec.gov/Archives/edgar/data/315700/000003540226001936/0000035402-26-001936-index.htm>
- N-PORT (fund B) — accession `0002071691-26-012466` (as of 2026-03-31)
  <https://www.sec.gov/Archives/edgar/data/1100663/000207169126012466/0002071691-26-012466-index.htm>

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