# Portfolio overlap — FBT vs IBB

Comparing **First Trust NYSE Arca Biotechnology Index Fund** (2026-03-31) and **iShares Biotechnology ETF** (2026-03-31).

- Shared positions: 28
- First Trust NYSE Arca Biotechnology Index Fund covered by iShares Biotechnology ETF: 0.4247722602655743585163659893
- iShares Biotechnology ETF covered by First Trust NYSE Arca Biotechnology Index Fund: 0.4247722602655743585163659895

## First Trust NYSE Arca Biotechnology Index Fund — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| MODERNA INC | 0.052582 | ✓ |
| UNITED THERAPEUTICS CORP DEL | 0.043554 | ✓ |
| ALKERMES PLC | 0.042325 | ✓ |
| GILEAD SCIENCES INC | 0.040860 | ✓ |
| AXSOME THERAPEUTICS INC | 0.038830 | ✓ |
| AMGEN INC | 0.038301 | ✓ |
| CORCEPT THERAPEUTICS INC | 0.038163 |  |
| KRYSTAL BIOTECH INC | 0.035082 | ✓ |
| BIOGEN INC | 0.034691 | ✓ |
| EXELIXIS INC | 0.034576 | ✓ |
| NEUROCRINE BIOSCIENCES INC | 0.034444 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.034438 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.034171 | ✓ |
| BIOMARIN PHARMACEUTICAL INC | 0.034020 | ✓ |
| ARGENX SE SPONSORED ADR | 0.032894 | ✓ |
| SAREPTA THERAPEUTICS INC | 0.032419 | ✓ |
| HALOZYME THERAPEUTICS INC | 0.031662 | ✓ |
| BIONTECH SE ADR | 0.031603 | ✓ |
| INCYTE CORP | 0.031267 | ✓ |
| BEONE MEDICINES LTD ADR | 0.031202 | ✓ |
| ILLUMINA INC | 0.031023 | ✓ |
| NATERA INC | 0.030303 | ✓ |
| ACADIA PHARMACEUTICALS INC | 0.029510 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.029494 | ✓ |
| BIO-TECHNE CORP | 0.028241 | ✓ |
| GENMAB A/S -SP ADR DEPOSITARY RECEIPT | 0.027803 | ✓ |
| VERACYTE INC | 0.027201 | ✓ |
| REPLIGEN CORP | 0.025074 | ✓ |
| BRUKER CORP | 0.023547 | ✓ |
| NEOGENOMICS INC | 0.020017 |  |
| DREY-GVT CSH-I | 0.000622 |  |
| DAIWA CAPITAL MARKETS AMERICA INC | 0.000083 |  |

## iShares Biotechnology ETF — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| BlackRock Cash Funds: Institutional, SL Agency Shares | 0.088091 |  |
| GILEAD SCIENCES INC | 0.070642 | ✓ |
| AMGEN INC | 0.068448 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.067866 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.065757 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.036382 | ✓ |
| INSMED INC | 0.029144 |  |
| ARGENX SE SPONSORED ADR | 0.028023 | ✓ |
| BIOGEN INC | 0.022451 | ✓ |
| NATERA INC | 0.022013 | ✓ |
| UNITED THERAPEUTICS CORP DEL | 0.021000 | ✓ |
| BEONE MEDICINES LTD ADR | 0.017638 | ✓ |
| INCYTE CORP | 0.015508 | ✓ |
| MODERNA INC | 0.015352 | ✓ |
| ILLUMINA INC | 0.015320 | ✓ |
| REVOLUTION MEDICINES INC | 0.014015 |  |
| ROIVANT SCIENCES LTD | 0.011325 |  |
| NEUROCRINE BIOSCIENCES INC | 0.010758 | ✓ |
| GENMAB A/S -SP ADR DEPOSITARY RECEIPT | 0.010706 | ✓ |
| BRIDGEBIO PHARMA INC | 0.010325 |  |
| IONIS PHARMACEUTICALS INC | 0.010161 |  |
| MEDPACE HOLDINGS INC | 0.009159 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.009127 |  |
| EXELIXIS INC | 0.009009 | ✓ |
| BIOMARIN PHARMACEUTICAL INC | 0.008955 | ✓ |
| Ascendis Pharma A/S | 0.008728 |  |
| PRAXIS PRECISION MEDICINES INC | 0.007056 |  |
| CHARLES RIVER LABS INTL INC | 0.007012 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.006863 |  |
| VAXCYTE INC | 0.006821 |  |
| BIO-TECHNE CORP | 0.006757 | ✓ |
| CYTOKINETICS INC | 0.006636 |  |
| HALOZYME THERAPEUTICS INC | 0.006300 | ✓ |
| AXSOME THERAPEUTICS INC | 0.006054 | ✓ |
| BIONTECH SE ADR | 0.005981 | ✓ |
| KRYSTAL BIOTECH INC | 0.005479 | ✓ |
| PROTAGONIST THERAPEUTICS INC | 0.005289 |  |
| REPLIGEN CORP | 0.005249 | ✓ |
| KYMERA THERAPEUTICS INC | 0.004874 |  |
| ALKERMES PLC | 0.004829 | ✓ |
| RHYTHM PHARMACEUTICALS INC | 0.004632 |  |
| Abivax SA SPONSORED ADS | 0.004593 |  |
| PTC THERAPEUTICS INC | 0.004536 |  |
| COGENT BIOSCIENCES INC | 0.004361 |  |
| ARCELLX INC | 0.004328 |  |
| TERNS PHARMACEUTICALS INC | 0.004224 |  |
| NUVALENT INC-A | 0.004088 |  |
| MIRUM PHARMACEUTICALS INC | 0.004072 |  |
| TEMPUS AI INC-A | 0.003928 |  |
| XENON PHARMACEUTICALS INC | 0.003906 |  |


## Sources

- N-PORT (fund A) — accession `0000940400-26-021488` (as of 2026-03-31)
  <https://www.sec.gov/Archives/edgar/data/1329377/000094040026021488/0000940400-26-021488-index.htm>
- N-PORT (fund B) — accession `0002071691-26-012466` (as of 2026-03-31)
  <https://www.sec.gov/Archives/edgar/data/1100663/000207169126012466/0002071691-26-012466-index.htm>

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