# Portfolio overlap — FBT vs FBDIX

Comparing **First Trust NYSE Arca Biotechnology Index Fund** (2026-03-31) and **Franklin Biotechnology Discovery Fund** (2026-01-31).

- Shared positions: 8
- First Trust NYSE Arca Biotechnology Index Fund covered by Franklin Biotechnology Discovery Fund: 0.2243406344523559420463660152
- Franklin Biotechnology Discovery Fund covered by First Trust NYSE Arca Biotechnology Index Fund: 0.2243406344523559420463660154

## First Trust NYSE Arca Biotechnology Index Fund — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| MODERNA INC | 0.052582 |  |
| UNITED THERAPEUTICS CORP DEL | 0.043554 |  |
| ALKERMES PLC | 0.042325 |  |
| GILEAD SCIENCES INC | 0.040860 | ✓ |
| AXSOME THERAPEUTICS INC | 0.038830 |  |
| AMGEN INC | 0.038301 | ✓ |
| CORCEPT THERAPEUTICS INC | 0.038163 |  |
| KRYSTAL BIOTECH INC | 0.035082 |  |
| BIOGEN INC | 0.034691 |  |
| EXELIXIS INC | 0.034576 |  |
| NEUROCRINE BIOSCIENCES INC | 0.034444 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.034438 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.034171 | ✓ |
| BIOMARIN PHARMACEUTICAL INC | 0.034020 |  |
| ARGENX SE SPONSORED ADR | 0.032894 | ✓ |
| SAREPTA THERAPEUTICS INC | 0.032419 |  |
| HALOZYME THERAPEUTICS INC | 0.031662 |  |
| BIONTECH SE ADR | 0.031603 |  |
| INCYTE CORP | 0.031267 |  |
| BEONE MEDICINES LTD ADR | 0.031202 | ✓ |
| ILLUMINA INC | 0.031023 |  |
| NATERA INC | 0.030303 |  |
| ACADIA PHARMACEUTICALS INC | 0.029510 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.029494 | ✓ |
| BIO-TECHNE CORP | 0.028241 |  |
| GENMAB A/S -SP ADR DEPOSITARY RECEIPT | 0.027803 |  |
| VERACYTE INC | 0.027201 |  |
| REPLIGEN CORP | 0.025074 |  |
| BRUKER CORP | 0.023547 |  |
| NEOGENOMICS INC | 0.020017 |  |
| DREY-GVT CSH-I | 0.000622 |  |
| DAIWA CAPITAL MARKETS AMERICA INC | 0.000083 |  |

## Franklin Biotechnology Discovery Fund — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| GILEAD SCIENCES INC | 0.059948 | ✓ |
| AMGEN INC | 0.046686 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.045691 | ✓ |
| JAZZ PHARMA PLC | 0.044323 |  |
| REGENERON PHARMACEUTICALS INC | 0.043066 | ✓ |
| ARGENX SE SPONSORED ADR | 0.039173 | ✓ |
| Franklin Institutional U.S. Government Money Market Fund | 0.033620 |  |
| PRAXIS PRECISION MEDICINES INC | 0.031293 |  |
| INSMED INC | 0.028167 |  |
| Ascendis Pharma A/S | 0.027923 |  |
| GUARDANT HEALTH INC | 0.027028 |  |
| PTC THERAPEUTICS INC | 0.026568 |  |
| TERNS PHARMACEUTICALS INC | 0.025378 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.021531 | ✓ |
| MIRUM PHARMACEUTICALS INC | 0.021143 |  |
| STRUCTURE THERAPEUTICS INC ADR | 0.019160 |  |
| REVOLUTION MEDICINES INC | 0.018681 |  |
| MINERALYS THERAPEUTICS INC | 0.018326 |  |
| ASTRAZENECA PLC SPONS ADR | 0.018108 |  |
| NEUROCRINE BIOSCIENCES INC | 0.017520 | ✓ |
| Abivax SA SPONSORED ADS | 0.017414 |  |
| EYEPOINT PHARMACEUTICALS INC | 0.016334 |  |
| IONIS PHARMACEUTICALS INC | 0.016164 |  |
| BRIDGEBIO PHARMA INC | 0.015289 |  |
| CENTESSA PHARMACEUTICALS LTD ADR | 0.014364 |  |
| LILLY ELI and CO | 0.013892 |  |
| OLEMA PHARMACEUTICALS INC | 0.013716 |  |
| ARCUTIS BIOTHERAPEUTICS INC | 0.012211 |  |
| SPYRE THERAPEUTICS INC | 0.012063 |  |
| BENITEC BIOPHARMA INC | 0.011538 |  |
| SYNDAX PHARMACEUTICALS INC | 0.011209 |  |
| CG ONCOLOGY INC | 0.010974 |  |
| ORUKA THERAPEUTICS INC | 0.010948 |  |
| DIANTHUS THERAPEUTICS INC | 0.010320 |  |
| CONTINEUM THERAPEUTICS INC CL A | 0.009178 |  |
| DYNE THERAPEUTICS INC | 0.008842 |  |
| ARS PHARMACEUTICALS INC | 0.008576 |  |
| Franklin Institutional US Government Money Market Fund | 0.008370 |  |
| NUVALENT INC-A | 0.007398 |  |
| SOLENO THERAPEUTICS INC | 0.006662 |  |
| ACHIEVE LIFE SCIENCES INC | 0.006270 |  |
| BICARA THERAPEUTICS INC | 0.006195 |  |
| AMYLYX PHARMACEUTICALS INC | 0.005984 |  |
| ALTO NEUROSCIENCE INC | 0.005972 |  |
| UNIQURE N.V. | 0.005853 |  |
| NEWAMSTERDAM PHARMA COMPANY NV | 0.005561 |  |
| TANGO THERAPEUTICS INC | 0.005436 |  |
| INVENTIVA SA UNSPON ADR | 0.005324 |  |
| APOGEE THERAPEUTICS INC | 0.005159 |  |
| ORIC PHARMACEUTICALS INC | 0.005123 |  |


## Sources

- N-PORT (fund A) — accession `0000940400-26-021488` (as of 2026-03-31)
  <https://www.sec.gov/Archives/edgar/data/1329377/000094040026021488/0000940400-26-021488-index.htm>
- N-PORT (fund B) — accession `0002071691-26-007599` (as of 2026-01-31)
  <https://www.sec.gov/Archives/edgar/data/872625/000207169126007599/0002071691-26-007599-index.htm>

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_Data sourced from U.S. SEC EDGAR filings (Forms N-PORT, N-CEN, and prospectus Risk/Return summaries). FundWatcher is not affiliated with the SEC._

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