# Portfolio overlap — FACTX vs SHSSX

Comparing **Fidelity Advisor Health Care Fund** (2026-01-31) and **BlackRock Health Sciences Opportunities Portfolio** (2026-02-27).

- Shared positions: 50
- Fidelity Advisor Health Care Fund covered by BlackRock Health Sciences Opportunities Portfolio: 0.3912921607769310240697564186
- BlackRock Health Sciences Opportunities Portfolio covered by Fidelity Advisor Health Care Fund: 0.3912921607769310240697564188

## Fidelity Advisor Health Care Fund — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| BOSTON SCIENTIFIC CORP | 0.069190 | ✓ |
| LILLY ELI and CO | 0.062493 | ✓ |
| DANAHER CORP | 0.060592 | ✓ |
| JOHNSON&JOHNSON | 0.034910 | ✓ |
| Fidelity Securities Lending Cash Central Fund | 0.030252 |  |
| ABBVIE INC | 0.029270 | ✓ |
| ARGENX SE SPONSORED ADR | 0.027328 | ✓ |
| UCB SA | 0.025285 | ✓ |
| Ascendis Pharma A/S | 0.024954 |  |
| CVS HEALTH CORP | 0.021117 | ✓ |
| MASIMO CORP | 0.020482 |  |
| EDWARDS LIFESCIENCES CORP | 0.020095 | ✓ |
| VEEVA SYSTEMS-A | 0.018735 | ✓ |
| THERMO FISHER SCIENTIFIC INC | 0.018640 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.016840 | ✓ |
| GILEAD SCIENCES INC | 0.016514 | ✓ |
| UNITEDHEALTH GRP | 0.015406 | ✓ |
| MERCK & CO | 0.015131 | ✓ |
| VIRIDIAN THERAPEUTICS INC | 0.014765 | ✓ |
| COGENT BIOSCIENCES INC | 0.014568 | ✓ |
| PENUMBRA INC | 0.013889 | ✓ |
| MODERNA INC | 0.013409 | ✓ |
| INSULET CORP | 0.013277 |  |
| IQVIA HOLDINGS INC | 0.012769 | ✓ |
| BRIGHTSPRING HEALTH SERVICES INC | 0.012651 |  |
| NUVALENT INC-A | 0.012276 | ✓ |
| INSMED INC | 0.011698 | ✓ |
| LEGEND BIOTECH CORP SPON ADR | 0.010714 |  |
| CRINETICS PHARMACEUTICALS INC | 0.010279 |  |
| ROCHE HOLDINGS AG (GENUSSCHEINE) | 0.010173 | ✓ |
| WAYSTAR HOLDING CORP | 0.010141 |  |
| MCKESSON CORP | 0.009918 | ✓ |
| CARIS LIFE SCIENCES INC | 0.009810 |  |
| ROYALTY PHARMA PLC | 0.009449 |  |
| STRUCTURE THERAPEUTICS INC ADR | 0.009234 |  |
| VAXCYTE INC | 0.008949 | ✓ |
| REPLIGEN CORP | 0.008911 | ✓ |
| STRYKER CORP | 0.008819 | ✓ |
| XENON PHARMACEUTICALS INC | 0.008441 |  |
| DISC MEDICINE INC | 0.008418 | ✓ |
| PRIVIA HEALTH GROUP INC | 0.008173 |  |
| INTUITIVE SURGICAL INC | 0.007941 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.007680 |  |
| ALIGNMENT HEALTHCARE INC | 0.007527 |  |
| MEDLINE INC-A | 0.007383 | ✓ |
| BIONTECH SE ADR | 0.007058 | ✓ |
| CG ONCOLOGY INC | 0.006645 | ✓ |
| CENTESSA PHARMACEUTICALS LTD ADR | 0.006230 |  |
| ORUKA THERAPEUTICS INC | 0.006126 | ✓ |
| 10X GENOMICS INC | 0.006025 |  |

## BlackRock Health Sciences Opportunities Portfolio — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| LILLY ELI and CO | 0.112658 | ✓ |
| JOHNSON&JOHNSON | 0.101544 | ✓ |
| ABBVIE INC | 0.040851 | ✓ |
| GILEAD SCIENCES INC | 0.039325 | ✓ |
| MERCK & CO | 0.035239 | ✓ |
| AMGEN INC | 0.034711 |  |
| UNITEDHEALTH GRP | 0.030228 | ✓ |
| INTUITIVE SURGICAL INC | 0.024425 | ✓ |
| ABBOTT LABS | 0.024092 |  |
| DANAHER CORP | 0.022937 | ✓ |
| THERMO FISHER SCIENTIFIC INC | 0.022604 | ✓ |
| EDWARDS LIFESCIENCES CORP | 0.022495 | ✓ |
| VERTEX PHARMACEUTICALS INC | 0.020646 |  |
| MEDTRONIC PLC | 0.019842 |  |
| STRYKER CORP | 0.019621 | ✓ |
| TEVA PHARMACEUTICAL IND ADR | 0.017890 |  |
| CENCORA INC | 0.015043 |  |
| BOSTON SCIENTIFIC CORP | 0.015007 | ✓ |
| ASTRAZENECA PLC | 0.014390 |  |
| ARGENX SE SPONSORED ADR | 0.014149 | ✓ |
| MCKESSON CORP | 0.011959 | ✓ |
| ROCHE HOLDINGS AG (GENUSSCHEINE) | 0.010694 | ✓ |
| BIOGEN INC | 0.010622 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.010486 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.010418 |  |
| BRISTOL-MYERS SQUIBB CO | 0.010404 |  |
| HCA HEALTHCARE INC | 0.010124 |  |
| BlackRock Cash Funds: Institutional, SL Agency Shares | 0.008737 |  |
| EXACT SCIENCES CORP | 0.008615 |  |
| RHYTHM PHARMACEUTICALS INC | 0.007596 |  |
| IDEXX LABS INC | 0.007451 |  |
| DEXCOM INC | 0.007411 |  |
| PENUMBRA INC | 0.006975 | ✓ |
| INSMED INC | 0.006842 | ✓ |
| Novartis AG | 0.006452 |  |
| INCYTE CORP | 0.006100 |  |
| MEDLINE INC-A | 0.006086 | ✓ |
| WATERS CORP | 0.006043 |  |
| BLKR-LIQ T-INS | 0.005199 |  |
| PROTAGONIST THERAPEUTICS INC | 0.005186 |  |
| AGILENT TECHNOLOGIES INC | 0.005006 |  |
| PFIZER INC | 0.004980 |  |
| NUVALENT INC-A | 0.004896 | ✓ |
| COGENT BIOSCIENCES INC | 0.004846 | ✓ |
| GUARDANT HEALTH INC | 0.004807 | ✓ |
| REVOLUTION MEDICINES INC | 0.004700 | ✓ |
| MODERNA INC | 0.004568 | ✓ |
| GALDERMA GROUP A | 0.004399 |  |
| CVS HEALTH CORP | 0.004365 | ✓ |
| ELEVANCE HEALTH INC | 0.004311 |  |


## Sources

- N-PORT (fund A) — accession `0000035402-26-001918` (as of 2026-01-31)
  <https://www.sec.gov/Archives/edgar/data/315700/000003540226001918/0000035402-26-001918-index.htm>
- N-PORT (fund B) — accession `0000940400-26-014709` (as of 2026-02-27)
  <https://www.sec.gov/Archives/edgar/data/844779/000094040026014709/0000940400-26-014709-index.htm>

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