# Portfolio overlap — BIPIX vs OTPIX

Comparing **BIOTECHNOLOGY ULTRASECTOR PROFUND** (2026-04-30) and **NASDAQ-100 PROFUND** (2026-04-30).

- Shared positions: 7
- BIOTECHNOLOGY ULTRASECTOR PROFUND covered by NASDAQ-100 PROFUND: 0.3015603079653690495245306340
- NASDAQ-100 PROFUND covered by BIOTECHNOLOGY ULTRASECTOR PROFUND: 0.3015603079653690495245306340

## BIOTECHNOLOGY ULTRASECTOR PROFUND — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| US ULTRA BOND CBT Sep25 | 0.286585 | ✓ |
| Invesco Government & Agency Portfolio, Institutional Class | 0.019693 |  |
| APELLIS PHARMACEUTICALS INC | 0.012941 |  |
| REVOLUTION MEDICINES INC | 0.011430 |  |
| TRAVERE THERAPEUTICS INC | 0.011242 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.009989 |  |
| TWIST BIOSCIENCE CORP | 0.009851 |  |
| SUMMIT THERAPEUTICS INC | 0.009735 |  |
| ALKERMES PLC | 0.009587 |  |
| TG THERAPEUTICS INC | 0.009511 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.009470 |  |
| BEAM THERAPEUTICS INC | 0.009185 |  |
| APOGEE THERAPEUTICS INC | 0.008766 |  |
| SCHOLAR ROCK HOLDING CORP | 0.008525 |  |
| PRAXIS PRECISION MEDICINES INC | 0.008479 |  |
| EXELIXIS INC | 0.008411 |  |
| MIRUM PHARMACEUTICALS INC | 0.008377 |  |
| UNITED THERAPEUTICS CORP DEL | 0.008283 |  |
| NATERA INC | 0.008282 |  |
| CRISPR Therapeutics A.G. Series A | 0.008279 |  |
| CELCUITY INC | 0.008279 |  |
| KRYSTAL BIOTECH INC | 0.008123 |  |
| PROTAGONIST THERAPEUTICS INC | 0.008102 |  |
| NEUROCRINE BIOSCIENCES INC | 0.008028 |  |
| INCYTE CORP | 0.007949 |  |
| CG ONCOLOGY INC | 0.007944 |  |
| CYTOKINETICS INC | 0.007940 |  |
| NUVALENT INC-A | 0.007916 |  |
| IONIS PHARMACEUTICALS INC | 0.007895 |  |
| BRIDGEBIO PHARMA INC | 0.007867 |  |
| VAXCYTE INC | 0.007858 |  |
| KYMERA THERAPEUTICS INC | 0.007854 |  |
| BIOGEN INC | 0.007848 |  |
| COGENT BIOSCIENCES INC | 0.007834 |  |
| PTC THERAPEUTICS INC | 0.007825 |  |
| INSMED INC | 0.007724 | ✓ |
| ALNYLAM PHARMACEUTICALS INC | 0.007628 | ✓ |
| ROIVANT SCIENCES | 0.007618 |  |
| HALOZYME THERAPEUTICS INC | 0.007563 |  |
| ARCUTIS BIOTHERAPEUTICS INC | 0.007442 |  |
| SPYRE THERAPEUTICS INC | 0.007420 |  |
| SOLENO THERAPEUTICS INC | 0.007364 |  |
| ABBVIE INC | 0.007330 |  |
| AMGEN INC | 0.007242 | ✓ |
| REGENERON PHARMACEUTICALS INC | 0.007210 | ✓ |
| ULTRAGENYX PHARMA INC | 0.007152 |  |
| ACADIA PHARMACEUTICALS INC | 0.007142 |  |
| RHYTHM PHARMACEUTICALS INC | 0.007138 |  |
| GILEAD SCIENCES INC | 0.007078 | ✓ |
| BIOMARIN PHARMACEUTICAL INC | 0.007059 |  |

## NASDAQ-100 PROFUND — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| US ULTRA BOND CBT Sep25 | 0.481902 | ✓ |
| NVIDIA CORP | 0.043728 |  |
| APPLE INC | 0.035924 |  |
| MICROSOFT CORP | 0.027308 |  |
| AMAZON.COM INC | 0.025662 |  |
| ALPHABET INC CL A | 0.020203 |  |
| ALPHABET INC CL C | 0.018726 |  |
| BROADCOM INC | 0.017846 |  |
| TESLA INC | 0.017169 |  |
| META PLATFORMS INC CL A | 0.016275 |  |
| WALMART INC | 0.016052 |  |
| MICRON TECHNOLOGY INC | 0.014489 |  |
| ADV MICRO DEVICE | 0.014387 |  |
| INTEL CORP | 0.011749 |  |
| COSTCO WHOLESALE CORP | 0.011213 |  |
| NETFLIX INC | 0.009839 |  |
| CISCO SYSTEMS INC | 0.008997 |  |
| LAM RESEARCH CORP | 0.008016 |  |
| PALANTIR TECHNOLOGIES INC | 0.007934 |  |
| APPLIED MATERIALS INC | 0.007794 |  |
| ZCS BRL 14.0087 05/12/25-01/04/27 CME | 0.006471 |  |
| TEXAS INSTRUMENTS INC | 0.006350 |  |
| LINDE PLC | 0.005782 |  |
| KLA CORP | 0.005708 |  |
| PEPSICO INC | 0.005392 |  |
| T-MOBILE US INC | 0.005364 |  |
| ANALOG DEVICES INC | 0.004890 |  |
| QUALCOMM INC | 0.004771 |  |
| AMGEN INC | 0.004646 | ✓ |
| INTUITIVE SURGICAL INC | 0.004045 |  |
| GILEAD SCIENCES INC | 0.004045 | ✓ |
| SANDISK CORPORATION | 0.004028 |  |
| SHOPIFY INC CL A | 0.003695 |  |
| WESTERN DIGITAL CORP | 0.003668 |  |
| SEAGATE TECHNOLO | 0.003656 |  |
| PALO ALTO NETWORKS INC | 0.003642 |  |
| MARVELL TECHNOLOGY INC | 0.003581 |  |
| APPLOVIN CORP | 0.003411 |  |
| HONEYWELL INTL INC | 0.003391 |  |
| THE BOOKING HOLDINGS INC | 0.003320 |  |
| ASML Holding NV - NY Reg Shares | 0.003151 |  |
| STARBUCKS CORP | 0.002988 |  |
| CONSTELLATION ENERGY CORP | 0.002821 |  |
| CROWDSTRIKE HOLDINGS INC | 0.002794 |  |
| VERTEX PHARMACEUTICALS INC | 0.002703 | ✓ |
| INTUIT INC | 0.002676 |  |
| ADOBE INC | 0.002498 |  |
| COMCAST CORP CL A | 0.002416 |  |
| MARRIOTT INTL-A | 0.002385 |  |
| SYNOPSYS INC | 0.002301 |  |


## Sources

- N-PORT (fund A) — accession `0000910472-26-009384` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1039803/000091047226009384/0000910472-26-009384-index.htm>
- N-PORT (fund B) — accession `0000910472-26-009378` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1039803/000091047226009378/0000910472-26-009378-index.htm>

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