# Portfolio overlap — BBC vs BIPIX

Comparing **Virtus LifeSci Biotech Clinical Trials ETF** (2026-04-30) and **BIOTECHNOLOGY ULTRASECTOR PROFUND** (2026-04-30).

- Shared positions: 76
- Virtus LifeSci Biotech Clinical Trials ETF covered by BIOTECHNOLOGY ULTRASECTOR PROFUND: 0.3014035017436343172060176649
- BIOTECHNOLOGY ULTRASECTOR PROFUND covered by Virtus LifeSci Biotech Clinical Trials ETF: 0.3014035017436343172060176650

## Virtus LifeSci Biotech Clinical Trials ETF — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| DREYFUS GOVT CASH MGMT FUND | 0.022336 |  |
| ERASCA INC | 0.021401 | ✓ |
| ENLIVEN THERAPEUTICS INC | 0.017690 |  |
| TANGO THERAPEUTICS INC | 0.016727 | ✓ |
| ORUKA THERAPEUTICS INC | 0.016394 | ✓ |
| SPYRE THERAPEUTICS INC | 0.016016 | ✓ |
| ALUMIS INC | 0.015544 |  |
| DIANTHUS THERAPEUTICS INC | 0.015075 | ✓ |
| KODIAK SCIENCES INC | 0.013209 | ✓ |
| REVOLUTION MEDICINES INC | 0.013206 | ✓ |
| CORVUS PHARMACEUTICALS INC | 0.013129 | ✓ |
| REZOLUTE INC | 0.012861 |  |
| DEFINIUM THERAPEUTICS INC | 0.012612 |  |
| CG ONCOLOGY INC | 0.011792 | ✓ |
| JADE BIOSCIENCES INC | 0.011783 |  |
| INHIBRX BIOSCIENCES INC | 0.011741 | ✓ |
| RELAY THERAPEUTICS INC | 0.011675 | ✓ |
| GH RESEARCH PLC | 0.011394 |  |
| NEKTAR THERAPEUTICS | 0.011245 |  |
| TYRA BIOSCIENCES INC | 0.011108 | ✓ |
| VIR BIOTECHNOLOGY INC | 0.011046 | ✓ |
| INTELLIA THERAPEUTICS INC | 0.010811 | ✓ |
| CENTESSA PHARMACEUTICALS LTD ADR | 0.010757 |  |
| ANAPTYSBIO INC | 0.010576 | ✓ |
| OMEROS CORP | 0.010405 |  |
| TECTONIC THERAPEUTIC INC | 0.010238 |  |
| ALLOGENE THERAPEUTICS INC | 0.010205 | ✓ |
| COMPASS Pathways PLC, ADR | 0.009724 |  |
| EDGEWISE THERAPEUTICS INC | 0.009482 |  |
| PALVELLA THERAPEUTICS INC | 0.009410 | ✓ |
| CAPRICOR THERAPEUTICS INC | 0.009335 | ✓ |
| VAXCYTE INC | 0.009303 | ✓ |
| PHARVARIS NV | 0.009285 |  |
| ARRIVENT BIOPHARMA INC | 0.009208 | ✓ |
| XENON PHARMACEUTICALS INC | 0.009201 |  |
| NEUROGENE INC | 0.009022 |  |
| SUMMIT THERAPEUTICS INC | 0.008835 | ✓ |
| AMYLYX PHARMACEUTICALS INC | 0.008835 |  |
| CELLDEX THERAPEUTICS INC | 0.008645 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.008574 | ✓ |
| ARCUS BIOSCIENCES INC | 0.008568 | ✓ |
| ANNEXON INC | 0.008544 | ✓ |
| TERNS PHARMACEUTICALS INC | 0.008507 |  |
| LIQUIDIA TECHNOLOGIES INC | 0.008497 |  |
| MONTE ROSA THERAPEUTICS INC | 0.008493 | ✓ |
| IMMUNOME INC | 0.008479 | ✓ |
| BICARA THERAPEUTICS INC | 0.008447 | ✓ |
| CELCUITY INC | 0.008336 | ✓ |
| IRONWOOD PHARMA CL A (PEND) | 0.008335 | ✓ |
| AbCellera Biologics Inc COM | 0.008293 |  |

## BIOTECHNOLOGY ULTRASECTOR PROFUND — top positions

| Security | Weight | Shared |
|----------|--------|--------|
| US ULTRA BOND CBT Sep25 | 0.286585 |  |
| Invesco Government & Agency Portfolio, Institutional Class | 0.019693 |  |
| APELLIS PHARMACEUTICALS INC | 0.012941 |  |
| REVOLUTION MEDICINES INC | 0.011430 | ✓ |
| TRAVERE THERAPEUTICS INC | 0.011242 |  |
| ARROWHEAD PHARMACEUTICALS INC | 0.009989 |  |
| TWIST BIOSCIENCE CORP | 0.009851 |  |
| SUMMIT THERAPEUTICS INC | 0.009735 | ✓ |
| ALKERMES PLC | 0.009587 |  |
| TG THERAPEUTICS INC | 0.009511 |  |
| MADRIGAL PHARMACEUTICALS INC | 0.009470 |  |
| BEAM THERAPEUTICS INC | 0.009185 | ✓ |
| APOGEE THERAPEUTICS INC | 0.008766 | ✓ |
| SCHOLAR ROCK HOLDING CORP | 0.008525 | ✓ |
| PRAXIS PRECISION MEDICINES INC | 0.008479 | ✓ |
| EXELIXIS INC | 0.008411 |  |
| MIRUM PHARMACEUTICALS INC | 0.008377 |  |
| UNITED THERAPEUTICS CORP DEL | 0.008283 |  |
| NATERA INC | 0.008282 |  |
| CRISPR Therapeutics A.G. Series A | 0.008279 |  |
| CELCUITY INC | 0.008279 | ✓ |
| KRYSTAL BIOTECH INC | 0.008123 |  |
| PROTAGONIST THERAPEUTICS INC | 0.008102 | ✓ |
| NEUROCRINE BIOSCIENCES INC | 0.008028 |  |
| INCYTE CORP | 0.007949 |  |
| CG ONCOLOGY INC | 0.007944 | ✓ |
| CYTOKINETICS INC | 0.007940 | ✓ |
| NUVALENT INC-A | 0.007916 | ✓ |
| IONIS PHARMACEUTICALS INC | 0.007895 |  |
| BRIDGEBIO PHARMA INC | 0.007867 |  |
| VAXCYTE INC | 0.007858 | ✓ |
| KYMERA THERAPEUTICS INC | 0.007854 | ✓ |
| BIOGEN INC | 0.007848 |  |
| COGENT BIOSCIENCES INC | 0.007834 | ✓ |
| PTC THERAPEUTICS INC | 0.007825 |  |
| INSMED INC | 0.007724 |  |
| ALNYLAM PHARMACEUTICALS INC | 0.007628 |  |
| ROIVANT SCIENCES | 0.007618 |  |
| HALOZYME THERAPEUTICS INC | 0.007563 |  |
| ARCUTIS BIOTHERAPEUTICS INC | 0.007442 |  |
| SPYRE THERAPEUTICS INC | 0.007420 | ✓ |
| SOLENO THERAPEUTICS INC | 0.007364 | ✓ |
| ABBVIE INC | 0.007330 |  |
| AMGEN INC | 0.007242 |  |
| REGENERON PHARMACEUTICALS INC | 0.007210 |  |
| ULTRAGENYX PHARMA INC | 0.007152 |  |
| ACADIA PHARMACEUTICALS INC | 0.007142 |  |
| RHYTHM PHARMACEUTICALS INC | 0.007138 |  |
| GILEAD SCIENCES INC | 0.007078 |  |
| BIOMARIN PHARMACEUTICAL INC | 0.007059 |  |


## Sources

- N-PORT (fund A) — accession `0000940400-26-024966` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1559109/000094040026024966/0000940400-26-024966-index.htm>
- N-PORT (fund B) — accession `0000910472-26-009384` (as of 2026-04-30)
  <https://www.sec.gov/Archives/edgar/data/1039803/000091047226009384/0000910472-26-009384-index.htm>

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